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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Shi, Zeya Tang, Siyuan Chen, Yuxiang Lee, Diana T-F Chair, Sek Y. Jiang, Bo Zhu, Xu Pan, Xiaoji Yang, Jinxu Qin, Yuelan |
| Description | Country affiliation: China Author Affiliation: Shi Z ( Surgical Intensive Care Unit, People's Hospital of Hunan Province, Changsha, Hunan, China.); Tang S ( Central South University School of Nursing, Changsha, Hunan, China.); Chen Y ( Department of Cummunity Nursing, Central South University School of Nursing, Changsha, Hunan, China.); Lee DT ( Department of Pharmacy, Biomedical Engineering Institute, Central South University, Changsha, Hunan, China.); Chair SY ( The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China.); Jiang B ( The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China.); Zhu X ( Hepatobiliary Surgery, People's Hospital of Hunan Province, Changsha, Hunan, China.); Pan X ( Surgical Intensive Care Unit, People's Hospital of Hunan Province, Changsha, Hunan, China.); Yang J ( Surgical Intensive Care Unit, People's Hospital of Hunan Province, Changsha, Hunan, China.); Qin Y ( Department of Nursing, College of Medicine, Luohe, China.) |
| Abstract | BACKGROUND: Stress-induced hyperglycaemia (SHG) can be observed in as high as 75% of critically ill patients, which can induce severe complications or adverse events. However, conventional intensive insulin therapy (CIIT) tends to induce hypoglycaemia and glucose variability. AIMS: This study investigated the clinical effects of a blood glycaemic control optimization programme (BGCOP) in patients with stress hyperglycaemia post hepatobiliary or pancreatic surgery. DESIGN: This study is a randomized, controlled, prospective clinical observation. METHODS: Eighty-six patients with postoperative SHG were randomly divided into a control and experimental groups. Participants in the control group underwent CIIT, while participants in the experimental group underwent blood glycaemic control optimization programme (BGCOP). A range of 7·8-10·0 mmol/L was designated as the target range for effective control of blood sugar. The validity index, adverse events and complications were compared between two groups. RESULTS: Compared to participants treated with CIIT, participants treated with BGCOP reached the target range of blood sugar levels more quickly (p = 0·000). The high glycaemic index (p = 0·000), incidence of hypoglycaemia (p = 0·011), and other adverse events as well as the incidence of abdominal infection (p = 0·026), incision infection (p = 0·044), and lung infection (p = 0·047) were significantly lower in participants who underwent the BGCOP than in patients treated with CIIT. CONCLUSION: BGCOP can more effectively control blood sugar levels compared with CIIT in patients with SHG after hepatobiliary or pancreatic surgery. RELEVANCE TO CLINICAL PRACTICE: This study provides a direction for blood glycaemic control in patients with stress hyperglycaemia post hepatobiliary or pancreatic surgery. |
| File Format | HTM / HTML |
| ISSN | 13621017 |
| Issue Number | 5 |
| Journal | Nursing in Critical Care |
| Volume Number | 21 |
| e-ISSN | 14785153 |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2016-09-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Critical Care Discipline Nursing |
| Content Type | Text |
| Resource Type | Article |
| Subject | Critical Care Nursing |
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