NDLI: Live-donor nephrectomy.

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Live-donor nephrectomy.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Rocca, Juan P. Davis, Eric Edye, Michael
Description	Country affiliation: United States Author Affiliation: Rocca JP ( Mount Sinai School of Medicine, New York, NY, USA. juan.rocca@mountsinai.org)
Abstract	Six decades after its first implementation, kidney transplantation remains the optimal therapy for end-stage renal disease requiring dialysis. Despite the incontrovertible mortality reduction and cost-effectiveness of kidney transplantation, the greatest remaining barrier to treatment of end-stage renal disease is organ availability. Although the waiting list of patients who stand to benefit from kidney transplantation grows at a rate proportional to the overall population and proliferation of diabetes and hypertension, the pool of deceased-donor organs available for transplantation experiences minimal to no growth. Because the kidney is uniquely suited as a paired organ, the transplant community's answer to this shortage is living donation of a healthy volunteer's kidney to a recipient with end-stage renal disease. This review details the history and evolution of living-donor kidney transplantation in the United States as well as advances the next decade promises. Laparoscopic donor nephrectomy has overcome many of the obstacles to living donation in terms of donor morbidity and volunteerism. Known donor risks in terms of surgical and medical morbidity are reviewed, as well as the ongoing efforts to delineate and mitigate donor risk in the context of accumulating recipient morbidity while on the waiting list.
File Format	HTM / HTML
ISSN	00272507
Issue Number	3
Volume Number	79
e-ISSN	19317581
Journal	Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine
Language	English
Publisher	Wiley
Publisher Date	2012-05-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Medicine Kidney Transplantation Methods Living Donors Nephrectomy Humans Kidney Failure, Chronic Risk Assessment Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Medicine

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