NDLI: The effects of duration of CO2 pneumoperitoneum on colonic anastomosis.

Please wait, while we are loading the content...

The effects of duration of CO2 pneumoperitoneum on colonic anastomosis.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Ozer, Ilter Ulas, Murat Ercan, Metin Ozogul, Yusuf B. Zengin, Neslihan Bostanci, E. Birol Ozel, Ummuhani Bilgihan, Ayse Akoglu, Musa
Description	Country affiliation: Turkey Author Affiliation: Ozer I ( Department of Gastrointestinal Surgery, Turkiye Yuksek Ihtisas Teaching and Research Hospital, Ankara, Turkey. ilterozer@yahoo.co)
Abstract	The aim of this study is to evaluate the effects of duration of carbon dioxide (CO(2)) pneumoperitoneum on experimental colonic anastomosis. Forty-eight male Sprague-Dawley rats were used. The rats were divided into three groups. The rats in group 1 (n = 16) underwent laparotomy and colonic anastomosis without pneumoperitoneum. The rats in group 2 (n = 16) and group 3 (n = 16) were subjected to 2 and 4 hours of 12 mm Hg pneumoperitoneum, respectively, before laparotomy and colonic anastomosis. Half of the rats were sacrified on the third postoperative day; and the other half, on the seventh postoperative day. A colonic segment including anastomosis site was resected for histopathologic and biochemical evaluation. On day 3, hydroxyproline levels of the three groups were similar. The edema score of group 2 was significantly higher than that of group 1, and the necrosis score was higher in group 2 than in group 3. The scores of the other histopathologic parameters were similar. On day 7, group 3 showed significantly higher hydroxyproline levels than group 1, and group 1 showed a higher necrosis score than group 3. In conclusion, CO(2) pneumoperitoneum of 12 mm Hg for 2 and 4 hours did not result in impaired healing of experimental colonic anastomosis.
File Format	HTM / HTML
ISSN	08941939
Issue Number	4
Volume Number	21
e-ISSN	15210553
Journal	Journal of Investigative Surgery
Language	English
Publisher	Taylor & Francis
Publisher Date	2008-07-01
Publisher Place	Great Britain (UK)
Access Restriction	Subscribed
Subject Keyword	Discipline General Surgery Anastomosis, Surgical Methods Colon Surgery Pneumoperitoneum, Artificial Animals Carbon Dioxide Metabolism Pathology Edema Hydroxyproline Male Necrosis Rats Rats, Sprague-dawley Time Factors Wound Healing Journal Article
Content Type	Text
Resource Type	Article
Subject	Surgery

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in