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Pathologic and clinical characteristics of elderly patients with breast cancer: a retrospective analysis of a multicenter study (Anatolian Society of Medical Oncology).

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Year: 2013 Volume: 98

Year: 2012 Volume: 97

Year: 1989 Volume: 74

Pathologic and clinical characteristics of elderly patients with breast cancer: a retrospective analysis of a multicenter study (Anatolian Society of Medical Oncology).

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Inal, Ali Akman, Tulay Yaman, Sebnem Ozturk, Selcuk Cemil Geredeli, Caglayan Bilici, Mehmet Inanc, Mevlude Harputoglu, Hakan Demirci, Umut Balakan, Ozan Cinkir, Havva Yesil Alici, Suleyman Colak, Dilsen Sonmez, Ozlem Uysal Goksel, Gamze Dogu, Gamze Gokoz Engin, Huseyin Unal, Olcun Umit Tamozlu, Tulay Buyukberber, Suleyman Boruban, Cem Melih Isikdogan, Abdurrahman
Description	Country affiliation: Turkey Author Affiliation: Inal A ( 1 Department of Medical Oncology, Dicle University, Diyarbakir, Turkey.)
Abstract	There is very little information about breast cancer characteristics, treatment choices, and survival among elderly patients. The purpose of this multicenter retrospective study was to examine the clinical, pathologic, and biologic characteristics of 620 breast cancer patients age 70 years or older. Between June 1991 and May 2012, 620 patients with breast cancer, recruited from 16 institutions, were enrolled in the retrospective study. Patients had smaller tumors at diagnosis; only 15% of patients had tumors larger than 5 cm. The number of patients who had no axillary lymph node involvement was 203 (32.7%). Ninety-three patients (15.0%) had metastatic disease at diagnosis. Patients were characterized by a higher fraction of pure lobular carcinomas (75.3%). The tumors of the elderly patients were also more frequently estrogen receptor (ER) positive (75.2%) and progesterone receptor (PR) positive (67.3%). The local and systemic therapies for breast cancer differed according to age. An association between age and overall survival has not been demonstrated in elderly patients with breast cancer. In conclusion, the biologic behavior of older patients with breast cancer differs from younger patients, and older patients receive different treatments.
File Format	HTM / HTML
ISSN	00208868
e-ISSN	25202456
DOI	10.9738/INTSURG-D-13-00010
Journal	International Surgery
Issue Number	1
Volume Number	99
Language	English
Publisher	International College of Surgeons
Publisher Date	2014-01-01
Publisher Place	Italy
Access Restriction	Open
Subject Keyword	Discipline General Surgery Adenocarcinoma Pathology Breast Neoplasms Mortality Therapy Axilla Breast Neoplasms, Male Combined Modality Therapy Lymphatic Metastasis Neoplasm Metastasis Prognosis Retrospective Studies Survival Analysis Multicenter Study
Content Type	Text
Resource Type	Article
Subject	Surgery

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