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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Joglekar, Neelam S. Deshpande, Swapna S. Sahay, Seema Ghate, Manisha V. Bollinger, Robert C. Mehendale, Sanjay M. |
| Spatial Coverage | India |
| Description | Country affiliation: India Author Affiliation: Joglekar NS ( National AIDS Research Institute, Indian Council of Medical Research, Pune, India.) |
| Abstract | BACKGROUND: Optimum comprehension of informed consent by research participants is essential yet challenging. This study explored correlates of lower comprehension of informed consent among 1334 participants of a cohort study aimed at estimating HIV incidence in Pune, India. METHODS: As part of the informed consent process, a structured comprehension tool was administered to study participants. Participants scoring ≥90% were categorised into the 'optimal comprehension group', whilst those scoring 80-89% were categorised into the 'lower comprehension group'. Data were analysed to identify sociodemographic and behavioural correlates of lower consent comprehension. RESULTS: The mean ± SD comprehension score was 94.4 ± 5.00%. Information pertaining to study-related risks was not comprehended by 61.7% of participants. HIV-negative men (adjusted OR [AOR] = 4.36, 95% CI 1.71-11.05) or HIV-negative women (AOR = 13.54, 95% CI 6.42-28.55), illiteracy (AOR= 1.65, 95% CI 1.19-2.30), those with a history of multiple partners (AOR = 1.73, 95% CI 1.12-2.66) and those never using condoms (AOR = 1.35, 95% CI 1.01-1.82) were more likely to have lower consent comprehension. CONCLUSIONS: We recommend exploration of domains of lower consent comprehension using a validated consent comprehension tool. Improved education in these specific domains would optimise consent comprehension among research participants. |
| File Format | HTM / HTML |
| ISSN | 18763413 |
| e-ISSN | 18763405 |
| DOI | 10.1093/inthealth/ihs009 |
| Journal | International Health |
| Issue Number | 1 |
| Volume Number | 5 |
| Language | English |
| Publisher | Oxford University Press |
| Publisher Date | 2013-03-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Discipline Public Health Discipline Tropical Medicine Physiology Hiv Infections Epidemiology Informed Consent Statistics & Numerical Data Research Subjects Cohort Studies Ethics, Research Odds Ratio Sex Distribution Socioeconomic Factors Research Support, N.i.h., Extramural |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health (social science) Public Health, Environmental and Occupational Health |
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