NDLI: Human infection with a highly pathogenic avian influenza A (H5N6) virus in Yunnan province, China.

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Human infection with a highly pathogenic avian influenza A (H5N6) virus in Yunnan province, China.

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Human infection with a highly pathogenic avian influenza A (H5N6) virus in Yunnan province, China.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Xu, Wen Li, Hong Jiang, Li
Description	Author Affiliation: Xu W ( a Yunnan Provincial Center for Disease Control and Prevention , Kunming , Yunnan , PR China.); Jiang L ( a Yunnan Provincial Center for Disease Control and Prevention , Kunming , Yunnan , PR China.)
Abstract	Highly pathogenic avian influenza A H5N6 virus has caused four human infections in China. This study reports the preliminary findings of the first known human case of H5N6 in Yunnan province. The patient initially developed symptoms of sore throat and coughing on 27 January 2015. The disease rapidly progressed to severe pneumonia, multiple organ dysfunctions and acute respiratory distress syndrome and the patient died on 6 February. Virological analysis determined that the virus belonged to H5 clade 2.3.4.4 and it has obtained partial ability for mammalian adaptation and amantadine resistance. Environmental investigation found H5 in 63% of the samples including poultry faeces, tissues, cage surface swabs and sewage from local live poultry markets by real-time RT-PCR. These findings suggest that the expanding and enhancing of surveillance in both avian and humans are necessary to monitor the evolution of H5 influenza virus and to facilitate early detection of suspected cases.
File Format	HTM / HTML
ISSN	23744235
Issue Number	6
Journal	Infectious Diseases
Volume Number	48
e-ISSN	23744243
Language	English
Publisher	Taylor & Francis
Publisher Date	2016-01-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Communicable Diseases
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Immunology and Microbiology Microbiology (medical)

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