NDLI: Pathology of extramedullary mastocytosis.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Doyle, Leona A. Hornick, Jason L.
Description	Author Affiliation: Doyle LA ( Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115 USA.); Hornick JL ( Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115 USA)
Abstract	Mastocytosis encompasses a group of clinically and pathologically heterogeneous disorders most commonly involving the skin, which typically takes the form of urticaria pigmentosa. Mastocytosis may also involve other organs, most often bone marrow, followed by gastrointestinal tract, liver, spleen, and lymph nodes. The presence of extracutaneous involvement by mastocytosis is a major diagnostic criterion for systemic disease. However, mast cell infiltrates are often subtle in skin and extracutaneous organs, and the histologic features of mastocytosis at different anatomic sites may be variable. This article reviews the pathologic features and clinical correlates of mastocytosis involving skin and other extramedullary sites.
File Format	HTM / HTML
ISSN	08898561
Issue Number	2
Volume Number	34
e-ISSN	15578607
Journal	Immunology and Allergy Clinics of North America
Language	English
Publisher	Elsevier
Publisher Date	2014-05-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Allergy and Immunology Carcinoma Diagnosis Gastrointestinal Neoplasms Mast Cells Pathology Mastocytosis Skin Stomach Adult Antigens, Cd Genetics Metabolism Child Gene Expression Humans Mutation Prognosis Proto-oncogene Proteins C-kit Tryptases Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Immunology and Allergy Immunology

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