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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Rafailidis, S. Ballas, K. Psarras, K. Pavlidis, T. Symeonidis, N. Marakis, G. Sakadamis, A. |
| Description | Country affiliation: Greece Author Affiliation: Rafailidis S ( 2nd Propedeutical Department of Surgery, Aristotle University of Thessaloniki, Thessaloniki, Greece. svrafail@otenet.gr) |
| Abstract | The Ewing sarcoma family of tumors (ESFT) includes classic Ewing sarcoma of the bone, extraosseous or soft tissue Ewing sarcoma, Askin tumors of the chest wall, and peripheral primitive neuroectodermal tumors of the bone and soft tissues. They share a common neural histogenesis, tumor genetics and biology. The genetic hallmark of the ESFT is the presence of t(11;22)(q24;q12), which creates the EWS/FLI1 fusion gene and results in the expression of a chimeric protein. Although Ewing tumors can occur at any age, the great majority are found in individuals less than 20 years of age. We herein report a case of gastric Ewing sarcoma in a 68-year-old male. This patient illustrates the second reported occurrence of primary Ewing sarcoma in the stomach and the first reported with the t(11;22)(q24;q12) gene translocation. |
| File Format | HTM / HTML |
| ISSN | 0014312X |
| Issue Number | 1 |
| Volume Number | 42 |
| e-ISSN | 14219921 |
| Journal | European Surgical Research |
| Language | English |
| Publisher | Karger |
| Publisher Date | 2009-01-01 |
| Publisher Place | Switzerland |
| Access Restriction | Subscribed |
| Subject Keyword | Discipline General Surgery Sarcoma, Ewing Pathology Stomach Neoplasms Aged Antigens, Cd Metabolism Cell Adhesion Molecules Chromosomes, Human, Pair 11 Genetics Chromosomes, Human, Pair 22 Humans Male Oncogene Proteins, Fusion Proto-oncogene Protein C-fli-1 Rna-binding Protein Ews Translocation, Genetic Case Reports Journal Article |
| Content Type | Text |
| Resource Type | Case study Article |
| Subject | Surgery |
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