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  1. Drug and Therapeutics Bulletin
  2. Year: 2011 Volume: 49
  3. Year: 2011 Volume: 49 Issue: 11
  4. Tyrosine kinase inhibitors for metastatic renal cell carcinoma.
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Year: 2017 Volume: 55
Year: 2016 Volume: 54
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Year: 2011 Volume: 49
Year: 2011 Volume: 49 Issue: 12
Year: 2011 Volume: 49 Issue: 11
Exceptionally difficult.
Single maintenance and reliever therapy (SMART) for asthma.
Tyrosine kinase inhibitors for metastatic renal cell carcinoma.
Year: 2011 Volume: 49 Issue: 10
Year: 2011 Volume: 49 Issue: 9
Year: 2011 Volume: 49 Issue: 8
Year: 2011 Volume: 49 Issue: 7
Year: 2011 Volume: 49 Issue: 6
Year: 2011 Volume: 49 Issue: 5
Year: 2011 Volume: 49 Issue: 4
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Year: 2011 Volume: 49 Issue: 2
Year: 2011 Volume: 49 Issue: 1
Year: 2010 Volume: 48
Year: 2009 Volume: 47
Year: 2008 Volume: 46
Year: 2007 Volume: 45

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Tyrosine kinase inhibitors for metastatic renal cell carcinoma.

Content Provider World Health Organization (WHO)-Global Index Medicus
Abstract Renal cell carcinoma accounts for 2-3% of all adult malignancies worldwide, and around 30% of patients with the condition present with advanced or metastatic disease.1,2 Until recently, cytokine therapy (e.g. interleukin-2 or interferon-alfa) was the standard treatment for metastatic renal cell carcinoma but provided only a small survival advantage (e.g. extending life by a median of 2.5 months).3 A key development has been the introduction of drugs known as receptor tyrosine kinase inhibitors, which include ▾sunitinib (Sutent-Pfizer), ▾sorafenib (Nexavar-Bayer) and ▾pazopanib (Votrient-GlaxoSmithKline). Here we review the evidence on the efficacy, tolerability and cost-effectiveness of these treatments in renal cell carcinoma.
File Format HTM / HTML
ISSN 00126543
Issue Number 11
Volume Number 49
e-ISSN 17555248
Journal Drug and Therapeutics Bulletin
Language English
Publisher BMJ Publishing Group
Publisher Date 2011-11-01
Publisher Place Great Britain (UK)
Access Restriction One Nation One Subscription (ONOS)
Subject Keyword Discipline Pharmacology Antineoplastic Agents Therapeutic Use Carcinoma, Renal Cell Drug Therapy Kidney Neoplasms Protein-tyrosine Kinases Antagonists & Inhibitors Angiogenesis Inhibitors Benzenesulfonates Economics Blood Supply Drug Costs Humans Indoles Neovascularization, Pathologic Prevention & Control Niacinamide Analogs & Derivatives Phenylurea Compounds Practice Guidelines As Topic Pyridines Pyrimidines Pyrroles Sulfonamides Vascular Endothelial Growth Factor A Metabolism Journal Article Review
Content Type Text
Resource Type Article
Subject Pharmacology (medical)
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