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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Heinrich, Sven P. Groten, Maresa Bach, Michael |
| Description | Author Affiliation: Heinrich SP ( Sektion Funktionelle Sehforschung, Klinik für Augenheilkunde, Universitätsklinikum Freiburg, Killianstr. 5, 79106, Freiburg, Germany, sven.heinrich@uniklinik-freiburg.de.) |
| Abstract | PURPOSE: Steady-state visual evoked potentials have various applications, including objective acuity testing. However, a non-monotonous spatial-frequency tuning (a 'notch') occurs at intermediate spatial frequencies in about half of the examinees. One possible reason lies in the temporal superposition of single-stimulus responses. This was investigated in 20 subjects. METHODS: Single-stimulus responses to checkerboard onsets were estimated through deconvolution of responses to m-sequence stimulation. Based on these, steady-state responses were predicted through superposition of temporally overlapping single-stimulus responses and compared to normally recorded steady-state responses. Discrepancies were analyzed in both the time and frequency domains. RESULTS: The agreement between predicted and recorded steady-state responses varied greatly among subjects, ranging from a good match including non-monotonous features of the tuning curve to substantial deviations. Although in some subjects the tuning of the recorded responses was better matched by the predicted responses than by the deconvolved m-sequence responses from which the prediction was computed, the correlation was not significantly different at the group level. In most subjects, there was only a small to moderate contribution of higher harmonics. The match between predicted and recorded responses was not always uniform across electrode locations. CONCLUSIONS: Our data are consistent with temporal superposition explaining an interindividually variable part of the checksize tuning curve without being its primary determinant. |
| File Format | HTM / HTML |
| ISSN | 00124486 |
| Issue Number | 1 |
| Volume Number | 131 |
| e-ISSN | 15732622 |
| Journal | Documenta Ophthalmologica |
| Language | English |
| Publisher | Springer |
| Publisher Date | 2015-08-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Ophthalmology Evoked Potentials, Visual Physiology Occipital Lobe Retina Adult Electroencephalography Female Humans Male Middle Aged Photic Stimulation Visual Pathways Young Adult Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology Physiology (medical) Sensory Systems |
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