NDLI: Comparison of the quality of lower limb magnetic resonance angiographies performed with different paramagnetic contrast agents in relation to body mass index and ejection fraction.

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Comparison of the quality of lower limb magnetic resonance angiographies performed with different paramagnetic contrast agents in relation to body mass index and ejection fraction.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Hrdina, Lukas Kocher, Martin Herman, Miroslav Cerna, Marie Kozak, Jiri Tudos, Zbynek Mahathmakanthi, Shankari Langova, Katerina
Description	Country affiliation: Czech Republic Author Affiliation: Hrdina L ( Department of Radiology, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic. Lukas.hrdina@post.cz)
Abstract	AIM: To compare the quality of magnetic resonance angiographies (MRAs) performed with different contrast agents and to evaluate the effect of body mass index (BMI) and ejection fraction (EF) on the quality of these MRAs. MATERIALS AND METHODS: 120 patients between the age of 43 and 86 years were subjected to MRAs with different contrast agents (Gadobutrolum, Dimeglumini gadobenas, Gadofosveset trisodium). Each patient's BMI was calculated, and EF was established using MR examination of the heart. Objective evaluations of the quality of the MRAs were done using abdominal fat-to-aorta enhancement ratio (FAR) comparisons. This ratio was then correlated with the patient's BMI and EF. Subjective evaluations of the quality of the MRAs were done by 5 blinded evaluators. Correlation analysis and analysis of variance were used for statistical assessement. RESULTS: There was no statistically significant difference in FAR for any of the contrast agent groups. There was a mesoscale correlation between a patient's BMI and FAR. However, no correlation was found between the EF and FAR for any of the contrast agent groups. The results of the subjective evaluation showed that there was no statistical difference in the quality of MRAs regardless of the contrast agent used. CONCLUSION: Subjectively there was no statistically significant difference in the quality of the MRAs. Irrespective of the type of contrast used or the patient's EF, the lower the BMI of a patient the higher the signal enhancement and hence the better the quality of the MRA produced in that patient.
File Format	HTM / HTML
ISSN	12138118
Journal	Biomedical Papers
Issue Number	2
Volume Number	156
Language	English
Publisher	Vydavatelství Univerzity Palackého
Publisher Date	2012-06-01
Publisher Place	Czech Republic
Access Restriction	Open
Subject Keyword	Discipline Medicine Body Mass Index Contrast Media Gadolinium Leg Blood Supply Magnetic Resonance Angiography Magnetic Resonance Imaging, Cine Organometallic Compounds Peripheral Arterial Disease Diagnosis Stroke Volume Aorta, Abdominal Pathology Heart Meglumine Analogs & Derivatives Physiopathology Comparative Study Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Medicine Biochemistry, Genetics and Molecular Biology

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