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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Zhou, Tian-Bao Yang, Guang-Shun |
| Description | Country affiliation: China Author Affiliation: Zhou TB ( The Hepatic Surgery Center, The Affiliated Ningbo No. 2 Hospital, Ningbo University School of Medicine, Ningbo, China. zhoutb68@126.com) |
| Abstract | The presently known cytokines that participate in acute rejection of organ transplantation include four categories by order of function: inflammatory cytokines, immunospecific cytokines, inflammatory cell activating cytokines and growth cytokines. Of them, growth cytokines that directly induce division, proliferation and migration of endothelial cells mainly include the vascular endothelial growth factor (VEGF) family and the fibroblast growth factor (FGF) family [1]. Recent studies [2] showed that interactions and time overlap of inflammatory cell infiltration and angiogenesis are the main mechanisms that induce acute rejection (AR) following organ transplantation, which has been demonstrated by the clinical fact that AR symptoms after liver transplantation could only be relieved by combination use of drugs for improving micro vessels and those for improving micro bile ducts. This article is a review of VEGF that mediates inflammatory cell infiltration and angiogenesis in the portal area [3]. |
| File Format | HTM / HTML |
| ISSN | 09663274 |
| Issue Number | 4 |
| Volume Number | 25 |
| e-ISSN | 18785492 |
| Journal | Transplant Immunology |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2011-12-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Transplantation Discipline Immunology Endothelial Cells Immunology Graft Rejection Liver Transplantation Liver Neovascularization, Pathologic Vascular Endothelial Growth Factor A Animals Cell Movement Pathology Humans Transplantation, Homologous Journal Article Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Immunology and Allergy Transplantation Immunology |
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