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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Zemrak, Filip Petersen, Steffen E. |
| Description | Country affiliation: United kingdom Author Affiliation: Zemrak F ( Centre for Advanced Cardiovascular Imaging, William Harvey Research Institute, Queen Mary, University of London, Barts, UK.) |
| Abstract | Cardiovascular magnetic resonance (CMR) has a recognized role in diagnosing and monitoring coronary artery disease (CAD). Multiple studies have shown that CMR can predict adverse outcomes. We reviewed contemporary available literature to establish the role of CMR with late gadolinium enhancement (LGE) in predicting mortality and major adverse cardiac events (MACEs) in patients with CAD. Meta-analysis of available prospective studies showed that the presence of LGE increases the hazards of death by more than 4 times and of MACE by almost 4 times. The size of LGE (per gram or percent) increases the hazards of death and MACE by 4% and 5%, respectively. The presence and size of LGE predict mortality and MACE in CAD. Various parameters derived from LGE images enhance the predictive value. Large randomized controlled trials are needed to establish the actual value of LGE and other derived parameters in the wider population. |
| File Format | HTM / HTML |
| ISSN | 00330620 |
| Issue Number | 3 |
| Volume Number | 54 |
| e-ISSN | 18731740 |
| Journal | Progress in Cardiovascular Diseases |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2011-11-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Cardiology Cardiovascular Diseases Etiology Contrast Media Coronary Artery Disease Diagnosis Gadolinium Magnetic Resonance Imaging Mortality Complications Humans Predictive Value Of Tests Prognosis Risk Assessment Risk Factors Severity Of Illness Index Journal Article Meta-analysis Research Support, Non-u.s. Gov't Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cardiology and Cardiovascular Medicine |
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