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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Gilchrist, Laura Tanner, Lynn |
| Description | Author Affiliation: Gilchrist L ( Cancer and Blood Disorders Program (Dr Gilchrist) and Rehabilitation Services (Ms Tanner), Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota) |
| Abstract | PURPOSE: Children treated with vincristine often develop chemotherapy-induced peripheral neuropathy (CIPN), but effects of CIPN on gait have not been reported. METHODS: Gait variables of 52 children/adolescents treated for non-central nervous system cancers with CIPN were compared with an age- and sex-matched control group. Gait data were collected via GaitRite walkway before and after completing a 6-minute walk test (6MWT). Ankle range-of-motion (ROM) measures, balance, and strength tests were also completed. RESULTS: Participants with CIPN had decreased velocity and step length. Ankle ROM and balance explained variability in step length. Both groups increased self-selected velocity after the 6MWT, but participants with cancer walked with slower velocity, shorter step length, and decreased cadence. Strength, neuropathy, and self-selected velocity measured before the 6MWT explained variability in 6MWT scores. CONCLUSIONS: Ankle ROM and balance are important factors when treating step length deficits, whereas strength is also an important consideration for walking capacity. |
| File Format | HTM / HTML |
| ISSN | 08985669 |
| e-ISSN | 1538005X |
| Journal | Pediatric Physical Therapy |
| Issue Number | 1 |
| Volume Number | 28 |
| Language | English |
| Publisher | Lippincott Williams & Wilkins |
| Publisher Date | 2016-01-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Physical and Rehabilitation Medicine Discipline Pediatrics Gait Disorders, Neurologic Chemically Induced Neoplasms Drug Therapy Vincristine Adverse Effects Adolescent Ankle Joint Child, Preschool Gait Physiology Muscle Strength Postural Balance Range Of Motion, Articular Therapeutic Use Walking Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physical Therapy, Sports Therapy and Rehabilitation Pediatrics, Perinatology and Child Health |
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