NDLI: A preliminary study of the Six-Item Screener in detecting cognitive impairment.

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A preliminary study of the Six-Item Screener in detecting cognitive impairment.

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A preliminary study of the Six-Item Screener in detecting cognitive impairment.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Chen, Mei-Rong Guo, Qi-Hao Cao, Xin-Yi Hong, Zhen Liu, Xiao-Hong
Description	Country affiliation: China Author Affiliation: Chen MR ( Department of Neurology, People's Hospital of Putuo District, Shanghai, China.)
Abstract	OBJECTIVE: The present retrospective study was to explore the clinical value of Six-Item Screener (SIS), which is constituted by 6 items from mini-mental status examination (MMSE), to identify cognitive impairment. METHODS: A total number of 1976 patients aged over 50 years, from the Memory Clinic of Huashan Hospital were employed in a battery of neuropsychological tests including MMSE. Subjects with severe conditions, unable to cooperate, or having been previously enrolled, were excluded from this study. The employed subjects were divided into 3 groups: subjective memory complaints (SMCs) (475 cases), patients with mild cognitive impairment (MCI) (440 cases), and patients with Alzheimer's disease (AD) (1061 cases, including 555 mild, 339 moderate, and 167 severe). A total score of MMSE and a score of SIS composed of date, month, year, three-word delayed recall from MMSE were calculated. Data were analyzed based on educational background. RESULTS: The cut-off of SIS score was <2 for illiterate, <3 for elementary, and <4 for junior high school or above. The sensitivity and specificity of SIS for detecting mild AD were 88.5% and 78.3%, respectively, with an overall accuracy of 83.8%, while for detecting MCI, the sensitivity and specificity were 34.3% and 90.1%, respectively, with an overall accuracy of 63.2%. CONCLUSION: SIS is an effective and reliable instrument for dementia detection in outpatient department. However, it has limited value for MCI identification.
File Format	HTM / HTML
ISSN	16737067
Issue Number	4
Volume Number	26
e-ISSN	19958218
Journal	Neuroscience Bulletin
Language	English
Publisher	Springer
Publisher Date	2010-08-01
Publisher Place	China
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Neurology Cognition Disorders Diagnosis Mass Screening Methods Mental Status Schedule Neuropsychological Tests Age Factors Aged Aged, 80 And Over Alzheimer Disease Complications Educational Status Female Humans Male Memory Disorders Mental Recall Physiology Middle Aged Sex Factors Journal Article
Content Type	Text
Resource Type	Article
Subject	Neuroscience Physiology Medicine

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