NDLI: Clinical impact of Clostridium difficile colonization.

Please wait, while we are loading the content...

Elderly infection in the community due to ST5/SCCmecII methicillin-resistant Staphylococcus aureus (the New York/Japan clone) in Japan: Panton-Valentine leukocidin-negative necrotizing pneumonia.

Pachydermodactyly: Three new cases in Taiwan.

Comparative antimicrobial efficacy of alcohol-based hand rub and conventional surgical scrub in a medical center.

Pyogenic liver abscess among children in a medical center in Central Taiwan.

Changing epidemiology of candidemia in a medical center in middle Taiwan.

Prevalence of and associated factors with chronic kidney disease in human immunodeficiency virus-infected patients in Taiwan.

Efficacy of ventilator-associated pneumonia care bundle for prevention of ventilator-associated pneumonia in the surgical intensive care units of a medical center.

Role of QuantiFERON-TB-Gold In Tube assay for active and latent tuberculosis infection in investigation of tuberculosis outbreak in a university.

Evolving trends of neonatal and childhood bacterial meningitis in northern Taiwan.

The mutations of katG and inhA genes of isoniazid-resistant Mycobacterium tuberculosis isolates in Taiwan.

Risk factors for levofloxacin resistance in Stenotrophomonas maltophilia from respiratory tract in a regional hospital.

Risk factors of community-onset urinary tract infections caused by plasmid-mediated AmpC ß-lactamase-producing Enterobacteriaceae.

Clinical and microbiological characteristics of peritoneal dialysis-related peritonitis caused by Klebsiella pneumoniae in southern Taiwan.

Liver abscess caused by Klebsiella pneumoniae in a red-footed tortoise.

Malakoplakia in a patient with complicated urinary tract infection caused by extended-spectrum ß-lactamase-producing Escherichia coli.

Characterization of bla(OxA-23) gene regions in isolates of Acinetobacter baumannii.

Phenotypes of Escherichia coli isolated from urine: Differences between extended-spectrum ß-lactamase producers and sensitive strains.

Clinical impact of Clostridium difficile colonization.

Year: 2015 Volume: 48 Issue: 2

Year: 2015 Volume: 48 Issue: 1

Year: 2014 Volume: 47

Year: 2013 Volume: 46

Year: 2012 Volume: 45

Year: 2011 Volume: 44

Year: 2010 Volume: 43

Clinical impact of Clostridium difficile colonization.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Hung, Yuan-Pin Lee, Jen-Chieh Lin, Hsiao-Ju Liu, Hsiao-Chieh Wu, Yi-Hui Tsai, Pei-Jane Ko, Wen-Chien
Description	Country affiliation: Taiwan Author Affiliation: Hung YP ( Department of Internal Medicine, Ministry of Health & Welfare, Tainan, Taiwan); Lee JC ( Department of Internal Medicine, National Cheng Kung University, Medical College and Hospital, Tainan, Taiwan.); Lin HJ ( Department of Internal Medicine, Ministry of Health & Welfare, Tainan, Taiwan); Liu HC ( Department of Internal Medicine, Ministry of Health & Welfare, Tainan, Taiwan.); Wu YH ( Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan.); Tsai PJ ( Department of Medical Laboratory Science and Biotechnology, National Cheng Kung University, Medical College, Tainan, Taiwan); Ko WC ( Department of Internal Medicine, National Cheng Kung University, Medical College and Hospital, Tainan, Taiwan. Electronic address: winston3415@gmail.com.)
Abstract	Clostridium difï¬ cile can cause antibiotic-associated diarrhea in hospitalized patients. Asymptomatic colonization by C. difficile is common during the neonatal period and early infancy, ranging from 21% to 48%, and in childhood. The colonization rate of C. difficile in adult hospitalized patients shows geographic variation, ranging from 4.4% to 23.2%. Asymptomatic carriage in neonates caused no further disease in many studies, whereas adult patients colonized with toxigenic C. difficile were prone to the subsequent development of C. difficile-associated diarrhea (CDAD). However, the carriage of nontoxigenic C. difficile strains appears to prevent CDAD in hamsters and humans. Risk factors for C. difficile colonization include recent hospitalization, exposure to antimicrobial agents or gastric acid-suppressing drugs (such as proton-pump inhibitors and H2 blockers), a history of CDAD or cytomegalovirus infection, the presence of an underlying illness, receipt of immunosuppressants, the presence of antibodies against toxin B, and Toll-like receptor 4 polymorphisms. Asymptomatic C. difficile carriers are associated with significant skin and environmental contamination, similar to those with CDAD, and contact isolation and hand-washing practices should therefore be employed as infection control policies for the prevention of C. difficile spread. Treating patients with asymptomatic C. difficile colonization with metronidazole or vancomycin is not suggested by the currently available evidence. In conclusion, asymptomatic C. difficile colonization may lead to skin and environmental contamination by C. difficile, but more attention should be paid to the clinical impact of those with C. difficile colonization.
File Format	HTM / HTML
ISSN	16841182
e-ISSN	19959133
Journal	Journal of Microbiology, Immunology and Infection
Issue Number	3
Volume Number	48
Language	English
Publisher	Elsevier
Publisher Date	2015-06-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Discipline Microbiology Discipline Immunology Carrier State Epidemiology Clostridium Infections Clostridium Difficile Isolation & Purification Cross Infection Diarrhea Animals Bacterial Toxins Metabolism Microbiology Cricetinae Disease Models, Animal Risk Factors Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Immunology and Microbiology Immunology and Allergy Microbiology (medical)

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Risk factors for Clostridium difficile-associated diarrhea among hospitalized adults with fecal toxigenic C. difficile colonization.

Fluoroquinolone use and Clostridium difficile-associated diarrhea.

Clinical manifestations of Clostridium difficile infection in a medical center in Taiwan.

Clostridium difficile in children: colonisation and disease.

Clostridium difficile infection at a medical center in southern Taiwan: incidence, clinical features and prognosis.

Vaccination against Clostridium difficile using toxin fragments: Observations and analysis in animal models.

Changing incidence and clinical manifestations of Clostridium difficile-associated diarrhea detected by combination of glutamate dehydrogenase and toxin assay in Northern Taiwan.

Vaccines against Clostridium difficile.

Is gastrointestinal endoscopy a risk factor for Clostridium difficile associated diarrhea?

Clinical impact of Clostridium difficile colonization.

Similar Documents

Risk factors for Clostridium difficile-associated diarrhea among hospitalized adults with fecal toxigenic C. difficile colonization.

Fluoroquinolone use and Clostridium difficile-associated diarrhea.

Clinical manifestations of Clostridium difficile infection in a medical center in Taiwan.

Clostridium difficile in children: colonisation and disease.

Clostridium difficile infection at a medical center in southern Taiwan: incidence, clinical features and prognosis.

Vaccination against Clostridium difficile using toxin fragments: Observations and analysis in animal models.

Changing incidence and clinical manifestations of Clostridium difficile-associated diarrhea detected by combination of glutamate dehydrogenase and toxin assay in Northern Taiwan.

Vaccines against Clostridium difficile.

Is gastrointestinal endoscopy a risk factor for Clostridium difficile associated diarrhea?

Clinical impact of Clostridium difficile colonization.