NDLI: Factors influencing diagnosis of colorectal cancer: a hospital-based survey in China.

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Factors influencing diagnosis of colorectal cancer: a hospital-based survey in China.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Deng, Shang Xin An, Wei Gao, Jie Yin, Jie Cai, Quan Cai Yang, Ming Hong, Shang You Fu, Xin Xin Yu, En Da Xu, Xiao Dong Zhu, Wei Li, Zhao Shen
Spatial Coverage	China
Description	Country affiliation: China Author Affiliation: Deng SX ( Department of Gastroenterology, Lanzhou General Hospital of Chinese People's Liberation Army, Lanzhou, Gansu Province, China.)
Abstract	OBJECTIVE: To investigate the diagnostic status of colorectal cancer (CRC) and the influence of early diagnosis and cancer stage in a tertiary care hospital in China. METHODS: Face-to-face interviews were conducted in 364 consecutive CRC patients who had never participated in CRC screening. Initial symptoms, diagnosis and treatment delay were determined using a questionnaire. Factors influencing diagnostic status were analyzed using univariate analysis and logistic regression model. RESULTS: A total of 307 patients were enrolled, in which 128 were with colon cancer and 179 with rectal cancer. The duration of diagnosis delay was significant longer than that of treatment delay. Unlike rectal cancer, colon cancer was likely to be treated at an advanced stage with a short interval between symptom onset and treatment. Colon cancer patients with a history of biliary tract or gallbladder stones, aged ≥ 50 years and with abdominal mass or intestinal obstruction as the initial symptom were diagnosed and treated much earlier. In rectal cancer, women and non-smokers were diagnosed and treated quickly. Factors correlated with early cancer stage were found in colon cancer, including bloody stool as the initial symptom (OR = 2.63, 95% CI 1.08-6.25, P = 0.034) and a history of appendectomy (OR = 4.00, 95% CI 1.15-14.29, P = 0.029). CONCLUSIONS: The factors contributing to early cancer detection were identified but their clinical value is limited. Diagnosis by symptoms suggesting CRC needs to be improved and CRC screening should be vigorously promoted.
File Format	HTM / HTML
ISSN	17512972
Issue Number	10
Volume Number	13
e-ISSN	17512980
Journal	Journal of Digestive Diseases
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2012-10-01
Publisher Place	Australia
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Gastroenterology Colonic Neoplasms Pathology Early Detection Of Cancer Gastrointestinal Hemorrhage Etiology Intestinal Obstruction Rectal Neoplasms Abdominal Pain Age Factors Appendectomy China Complications Diagnosis Female Gallstones Hospitals Humans Interviews As Topic Logistic Models Male Middle Aged Neoplasm Staging Sex Factors Time Factors Journal Article
Content Type	Text
Resource Type	Article
Subject	Gastroenterology

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