NDLI: Methylmercury and elemental mercury differentially associate with blood pressure among dental professionals.

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Methylmercury and elemental mercury differentially associate with blood pressure among dental professionals.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Goodrich, Jaclyn M. Wang, Yi Gillespie, Brenda Werner, Robert Franzblau, Alfred Basu, Niladri
Spatial Coverage	Michigan
Description	Country affiliation: United States Author Affiliation: Goodrich JM ( Department of Environmental Health Sciences, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109, USA.)
Abstract	Methylmercury-associated effects on the cardiovascular system have been documented though discrepancies exist, and most studied populations experience elevated methylmercury exposures. No paper has investigated the impact of low-level elemental (inorganic) mercury exposure on cardiovascular risk in humans. The purpose of this study was to increase understanding of the association between mercury exposure (methylmercury and elemental mercury) and blood pressure measures in a cohort of dental professionals that experience background exposures to both mercury forms. Dental professionals were recruited during the 2010 Michigan Dental Association Annual Convention. Mercury levels in hair and urine samples were analyzed as biomarkers of methylmercury and elemental mercury exposure, respectively. Blood pressure (systolic, diastolic) was measured using an automated device. Distribution of mercury in hair (mean, range: 0.45, 0.02-5.18 µg/g) and urine (0.94, 0.03-5.54 µg/L) correspond well with the US National Health and Nutrition Examination Survey. Linear regression models revealed significant associations between diastolic blood pressure (adjusted for blood pressure medication use) and hair mercury (n=262, p=0.02). Urine mercury results opposed hair mercury in many ways. Notably, elemental mercury exposure was associated with a significant systolic blood pressure decrease (n=262, p=0.04) that was driven by the male population. Associations between blood pressure and two forms of mercury were found at exposure levels relevant to the general population, and associations varied according to type of mercury exposure and gender.
File Format	HTM / HTML
ISSN	14384639
e-ISSN	1618131X
DOI	10.1016/j.ijheh.2012.03.001
Journal	International Journal of Hygiene and Environmental Health
Issue Number	2
Volume Number	216
Language	English
Publisher	Elsevier
Publisher Date	2013-03-01
Publisher Place	Germany
Access Restriction	Open
Subject Keyword	Discipline Environmental Health Air Pollutants, Occupational Blood Pressure Dental Staff Dentists Mercury Methylmercury Compounds Environmental Monitoring Hair Chemistry Michigan Occupational Exposure Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Public Health, Environmental and Occupational Health

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Methylmercury and elemental mercury differentially associate with blood pressure among dental professionals.

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Methylmercury and elemental mercury differentially associate with blood pressure among dental professionals

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Methylmercury and elemental mercury differentially associate with blood pressure among dental professionals.