NDLI: Thrombocytopenia induced by both aspirin and clopidogrel in the same patient.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Hu, Yunzhen Yuan, Min Lu, Xiaoyang
Description	Country affiliation: China Author Affiliation: Hu Y ( Department of Pharmacy, Zhejiang University, Hangzhou, China.)
Abstract	Aspirin and clopidogrel are used widely as antiplatelet agents due to their efficacy, safety, and tolerability. In rare cases, these agents can cause thrombotic thrombocytopenic purpura, but no report has documented severe thrombocytopenia in response to both drugs in the same patient. A 73-year old female developed severe thrombocytopenia following treatment with clopidogrel. Platelet count recovered within 6 months of drug withdrawal without additional thrombopoietic therapies. Seven months after the last dose of clopidogrel, thrombocytopenia recurred on aspirin therapy. Again, platelet count rebounded gradually and independently. This case suggests that some patients who experience thrombocytopenia in response to one antiplatelet agent may react similarly to other antiplatelet agents.
File Format	HTM / HTML
ISSN	09461965
Issue Number	3
Volume Number	51
Journal	Int. Journal of Clinical Pharmacology and Therapeutics
Language	English
Publisher	Dustri-Verlag
Publisher Date	2013-03-01
Publisher Place	Germany
Access Restriction	Subscribed
Subject Keyword	Discipline Pharmacology Aspirin Adverse Effects Platelet Aggregation Inhibitors Thrombocytopenia Chemically Induced Ticlopidine Analogs & Derivatives Aged Female Humans Case Reports Journal Article
Content Type	Text
Resource Type	Case study Article
Subject	Pharmacology Pharmacology (medical)

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