NDLI: Surgical management of hepatic metastases of colorectal cancer.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Smith, J. Joshua D'Angelica, Michael I.
Description	Country affiliation: United States Author Affiliation: Smith JJ ( Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.); D'Angelica MI ( Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. Electronic address: dangelim@mskcc.org.)
Abstract	For the 20% of patients with resectable colorectal liver metastases (CRLM), hepatic resection is safe, effective and potentially curative. Factors related to the primary and metastatic tumors individually and in clinical risk-scoring schemes are the best prognostic factors, although it is difficult to define patient groups with resectable, liver-limited CRLM that should be excluded from surgery. Systemic chemotherapy for metastatic colorectal cancer has improved but does not improve overall survival as adjuvant therapy after resection. Conversion to complete resection with systemic and/or hepatic arterial infusion chemotherapy is an appropriate goal for patients with unresectable CRLM.
File Format	HTM / HTML
ISSN	08898588
Issue Number	1
Volume Number	29
e-ISSN	15581977
Journal	Hematology/Oncology Clinics of North America
Language	English
Publisher	Elsevier
Publisher Date	2015-02-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Hematology Discipline Oncology Colorectal Neoplasms Pathology Liver Neoplasms Secondary Surgery Diagnosis Epidemiology Combined Modality Therapy Disease Management Humans Morbidity Mortality Neoplasm Recurrence, Local Neoplasm Staging Prognosis Retreatment Treatment Outcome Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Hematology Oncology

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