Please wait, while we are loading the content...
Please wait, while we are loading the content...
| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Nilsson, J. R. |
| Description | Country affiliation: Denmark Author Affiliation: Nilsson JR ( Institute of Cell Biology and Anatomy, The Zoological Institutes, Copenhagen, Denmark.) |
| Abstract | The effects of 0.2-2.0 mM PtCl(4) have been investigated, the purpose was to test whether the compound would affect Tetrahymena in a manner similar to that of cis-dichlorodiammine-platinum(II), or cisplatin, which in 0.83 mM inhibits cell proliferation for 24 h and induces diminution of the inner mitochondrial membrane, as reported recently. During the first hour, the rate of cell proliferation was unaffected by platinic chloride; this period was followed by a lag of 1-1.5 h in 0.5-0.83 mM, of 5 h in 1.0 mM, and of about 24 h in 1.5-2.0 mM PtCl(4) before proliferation resumed at a decreased, but constant, rate. At the low concentrations, the rate of proliferation corresponded to half the rate of control cells, whereas only 1.00 and 0.56 cell doubling was completed after 24 h in 1.5 and 2.0 mM, respectively, and a large percentage of the cells were monsters. The normal cell shape was restored within 48 h. The rate of endocytosis was affected dose dependently, but not blocked completely in 0.5-2.0 mM PtCl(4). All treated cells contained small refractive granules, accumulating with time in growth-inhibited cells but remaining at a constant level in cells capable of proliferation. These granules are probably connected with cell detoxification as proposed previously. In contrast to cisplatin, PtCl(4) did not induce loss of the inner mitochondrial membrane, even after 24 h in 2.0 mM. |
| File Format | HTM / HTML |
| ISSN | 09324739 |
| Issue Number | 2 |
| Journal | European Journal of Protistology |
| Volume Number | 28 |
| e-ISSN | 16180429 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 1992-05-22 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Microbiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Microbiology |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|