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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Murphy, Patrick Brian Zoumot, Zaid Polkey, Michael Iain |
| Description | Country affiliation: United kingdom Author Affiliation: Murphy PB ( Lane Fox Clinical Respiratory Physiology Group, Guy's & St Thomas' NHS Foundation Trust, London, UK.); Zoumot Z ( NIHR Respiratory Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, Imperial College London, London, UK.); Polkey MI ( NIHR Respiratory Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, Imperial College London, London, UK. Electronic address: m.polkey@rbht.nhs.uk.) |
| Abstract | As parenchymal lung disease in chronic obstructive pulmonary disease becomes increasingly severe there is a diminishing prospect of drug therapies conferring clinically useful benefit. Lung volume reduction surgery is effective in patients with heterogenous upper zone emphysema and reduced exercise tolerance, and is probably underused. Rapid progress is being made in nonsurgical approaches to lung volume reduction, but use outside specialized centers cannot be recommended presently. Noninvasive ventilation given to patients with acute hypercapnic exacerbation of chronic obstructive pulmonary disease reduces mortality and morbidity, but the place of chronic non-invasive ventilatory support remains more controversial. |
| File Format | HTM / HTML |
| ISSN | 02725231 |
| Issue Number | 1 |
| Volume Number | 35 |
| e-ISSN | 15578216 |
| Journal | Clinics in Chest Medicine |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-03-01 |
| Publisher Place | United States |
| Access Restriction | Subscribed |
| Subject Keyword | Discipline Pulmonary Medicine Noninvasive Ventilation Pneumonectomy Pulmonary Disease, Chronic Obstructive Therapy Pulmonary Emphysema Surgery Bronchoscopy Humans Hypercapnia Lung Physiopathology Methods Journal Article Research Support, Non-u.s. Gov't Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pulmonary and Respiratory Medicine |
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