NDLI: Cooperative group research efforts in lung cancer: focus on early-stage non-small-cell lung cancer.

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Is there a role for positron emission tomography/computed tomography in the staging of small-cell lung cancer?

Cooperative group research efforts in lung cancer: focus on early-stage non-small-cell lung cancer.

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Bronchioloalveolar carcinoma: the case for two diseases.

Can positron emission tomography be used as a staging tool for small-cell lung cancer?

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Year: 2007 Volume: 8

Cooperative group research efforts in lung cancer: focus on early-stage non-small-cell lung cancer.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Wakelee, Heather Langer, Corey Vokes, Everett Schiller, Joan Baas, Paul Saijo, Nagahiro Adjei, Alex Shepherd, Frances Choy, Hak Gandara, David R.
Description	Country affiliation: United States Author Affiliation: Wakelee H ( Department of Medicine, Division of Oncology, Stanford Cancer Center, Stanford, California 94305-5826, USA. hwakelee@stanford.edu)
Abstract	Many of the most significant advances in the treatment of lung cancer have come from trials run within the cooperative group system. The leaders of the lung cancer section of each group interact throughout the year, but an annual lung cancer congress in Hawaii provides a forum for extensive discussions of ongoing and planned trials. This article is the first in a series that will focus on the key points of this discussion held at the 8th Annual Lung Cancer Congress in June 2007. Early-stage non-small-cell lung cancer trials are highlighted in this manuscript. Current work in adjuvant therapy is focused on exploring the use of bevacizumab in addition to chemotherapy for resected disease in a large Intergroup study and the use of more 'personalized' chemotherapy based on specific genomic or protein expression profiles of individual tumors in smaller exploratory studies. The question of postoperative radiation therapy is being addressed within the cooperative groups. Alternative approaches to surgery, such as lesser resections in smaller tumors and accelerated radiation including stereotactic radiosurgery, are also under investigation within this framework. Ongoing trials within the cooperative groups continue to drive steady improvement in the treatment of lung cancer and offer great promise for the future.
File Format	HTM / HTML
ISSN	15257304
Issue Number	1
Volume Number	9
e-ISSN	19380690
Journal	Clinical Lung Cancer
Language	English
Publisher	Elsevier
Publisher Date	2008-01-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Pulmonary Medicine Discipline Oncology Carcinoma, Non-small-cell Lung Therapy Lung Neoplasms Pathology Clinical Trials As Topic Cooperative Behavior Humans Neoplasm Staging Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Pulmonary and Respiratory Medicine Cancer Research Oncology

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