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Thyroid fine-needle aspiration cytology: performance data of neoplastic and malignant cases as identified from 1558 responses in the ASCP Non-GYN Assessment program thyroid fine-needle performance data.

Molecular characterization of 54 cases of false-negative fine-needle aspiration among 1347 papillary thyroid carcinomas.

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Thyroid fine-needle aspiration cytology: performance data of neoplastic and malignant cases as identified from 1558 responses in the ASCP Non-GYN Assessment program thyroid fine-needle performance data.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Eilers, Stan G. LaPolice, Paula Mukunyadzi, Perkins Kapur, Umesh Wendel Spiczka, Amy Shah, Ajay Saleh, Husain Adeniran, Adebowale Nunez, Amberly Balachandran, Indra Clark, Jennifer J. Lemon, Larry
Description	Author Affiliation: Eilers SG ( Mercy Medical Center, Cedar Rapids, Iowa.)
Abstract	BACKGROUND: Fine-needle aspiration of the thyroid is a common procedure, with an established role in reducing unnecessary thyroid surgery and identifying neoplasms and malignancies. METHODS: The study evaluated 1558 responses in the American Society for Clinical Pathology (ASCP) Non-GYN Assessment program of aspirates of thyroid neoplasms and malignancies and placed them into the following groups: group A (target or correct interpretation), group B (incorrect interpretation as a benign thyroid nodule), group C (incorrect interpretation malignant aspirate as thyroid neoplasm), and group D (malignant diagnosis with incorrect interpretation). In clinical practice, responses in groups A, C, and D would lead to surgical excision, whereas responses in group B would not. RESULTS: Of a total of 1558 responses, 78.5% of the responses were in group A, 8.5% in group B, 3.75% in group C, and 9.25% in group D. By individual diagnosis, the group rates were 86.5%, 0%, 11%, and 2.5% for anaplastic thyroid carcinoma; 83%, 5.5%, 4.25%, and 7.25% for papillary thyroid carcinoma; 79%, 7%, 6%, and 8% for medullary thyroid carcinoma; 83.5% 6.75%, 0%, and 9.75% for Hürthle cell neoplasm; and 61%, 22%, 0%, and 17% for follicular neoplasm in groups A, B, C, and D respectively. CONCLUSIONS: Fine-needle aspiration was effective in diagnosing thyroid neoplasms and malignancies and in separating thyroid nodules into surgical and nonsurgical categories. Data from a large group of cytology professionals showed good performance; however, there is room for improvement, especially in making specific diagnoses. In particular, follicular neoplasm and follicular variant of papillary thyroid carcinoma were challenging diagnoses for participants.
File Format	HTM / HTML
ISSN	1934662X
e-ISSN	19346638
DOI	10.1002/cncy.21440
Journal	Cancer Cytopathology
Issue Number	10
Volume Number	122
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2014-10-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Cytology Discipline Pathology Discipline Oncology Biopsy, Fine-needle Databases, Factual Thyroid Neoplasms Pathology Adenocarcinoma, Follicular Surgery Adenoma, Oxyphilic Carcinoma Carcinoma, Neuroendocrine Cytodiagnosis Diagnosis, Differential Immunohistochemistry Neoplasm Invasiveness Neoplasm Staging Risk Assessment Societies, Medical Diagnosis Thyroid Nodule Thyroidectomy Evaluation Studies
Content Type	Text
Resource Type	Article
Subject	Cancer Research Oncology

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Thyroid fine-needle aspiration cytology: Performance data of neoplastic and malignant cases as identified from 1558 responses in the ASCP Non-GYN Assessment program thyroid fine-needle performance data

Follicular lesions of the thyroid: a retrospective study of 1,348 fine needle aspiration biopsies.

Ultrasonography-guided core needle biopsy for the thyroid nodule: does the procedure hold any benefit for the diagnosis when fine-needle aspiration cytology analysis shows inconclusive results?

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Subclassification of 'atypia of undetermined significance' in thyroid fine-needle aspirates.

Potential pitfalls of needle tract effects on repeat thyroid fine-needle aspiration.

Fine Needle Aspiration Cytology of Thyroid Follicular Neoplasm: Cytohistologic Correlation and Accuracy

The role of thyroid fine-needle aspiration cytology in the pediatric population: an institutional experience.

Thyroid fine-needle aspiration cytology: performance data of neoplastic and malignant cases as identified from 1558 responses in the ASCP Non-GYN Assessment program thyroid fine-needle performance data.

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Thyroid fine-needle aspiration cytology: Performance data of neoplastic and malignant cases as identified from 1558 responses in the ASCP Non-GYN Assessment program thyroid fine-needle performance data

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Thyroid fine-needle aspiration cytology: performance data of neoplastic and malignant cases as identified from 1558 responses in the ASCP Non-GYN Assessment program thyroid fine-needle performance data.