NDLI: Fecal Lipid Excretion after Consumption of a Black Tea Polyphenol Containing Beverage-Randomized, Placebo-Controlled, Double-Blind, Crossover Study.

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Fecal Lipid Excretion after Consumption of a Black Tea Polyphenol Containing Beverage-Randomized, Placebo-Controlled, Double-Blind, Crossover Study.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Ashigai, Hiroshi Taniguchi, Yoshimasa Suzuki, Mihoko Ikeshima, Emiko Kanaya, Tomoka Zembutsu, Kanako Tomita, Shimpei Miyake, Mika Fukuhara, Ikuo
Description	Author Affiliation: Ashigai H ( Research Laboratories for Health Science & Food Technologies, Kirin Co., Ltd.)
Abstract	Obesity is a serious medical condition worldwide. Inhibition of lipid absorption is very important in preventing obesity. In a previous study, we found that postprandial elevation of triacylglycerol was suppressed by the intake of black tea polyphenol (BTP). We also reported that BTP caused lipid excretion into feces in an animal study. The present study is a clinical trial that examined lipid excretion. In this randomized, placebo-controlled, double-blind, crossover study, in the first test period participants were asked to drink either a beverage containing 55 mg BTP or a control beverage without BTP 3 times a day for 10 d. After an 11-d interval, for the second test period, they then drank the alternate test beverage 3 times a day for 10 d. During the test periods, the participants were asked to eat meals standardized according to calorie and fat content. Stool samples were obtained during the last 3 d of each test period for fecal lipid measurements. Total lipid excretion increased from 5.51±1.73 to 6.87±1.91 g/3 d after BTP intake in comparison with intake of the control beverage. These results indicated that BTP increased lipid excretion.
File Format	HTM / HTML
ISSN	09186158
e-ISSN	13475215
Journal	Biological & Pharmaceutical Bulletin
Issue Number	5
Volume Number	39
Language	English
Publisher	The Pharmaceutical Society of Japan J-STAGE
Publisher Date	2016-05-01
Publisher Place	Japan
Access Restriction	Open
Subject Keyword	Discipline Biochemistry Discipline Pharmacology
Content Type	Text
Resource Type	Article
Subject	Medicine Pharmacology Pharmaceutical Science

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