NDLI: The impact of Bacille Calmette-Guérin shortage on immunisation practice and policies in Europe - A Paediatric Tuberculosis Network European Trials Group (ptbnet) survey.

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The impact of Bacille Calmette-Guérin shortage on immunisation practice and policies in Europe - A Paediatric Tuberculosis Network European Trials Group (ptbnet) survey.

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The impact of Bacille Calmette-Guérin shortage on immunisation practice and policies in Europe - A Paediatric Tuberculosis Network European Trials Group (ptbnet) survey.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Kontturi, Antti Santiago, Begoña Tebruegge, Marc Von Both, Ulrich Salo, Eeva Ritz, Nicole
Description	Author Affiliation: Kontturi A ( Department of Paediatrics, Children's Hospital, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland); Santiago B ( Sección Enfermedades Infecciosas Pediátricas, Servicio de Pediatría, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain. Electronic address: bsantiagogarcia@gmail.com.); Tebruegge M ( Faculty of Medicine & Global Health Research Institute, University of Southampton, Southampton, UK); von Both U ( Division of Paediatric Infectious Diseases, Dr von Hauner Children's Hospital, LMU, Munich, Germany); Salo E ( Department of Paediatrics, Children's Hospital, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland. Electronic address: eeva.salo@hus.fi.); Ritz N ( Department of Paediatrics, The University of Melbourne, Parkville, Australia)
Abstract	BACKGROUND: Recent reports indicate an ongoing BCG shortage that may influence immunisation practice. This study aimed to determine current availability of BCG vaccine across Europe, and implications on immunisation practices and policies in Europe. METHODS: Web-based survey among Paediatric Tuberculosis Network European Trials Group (ptbnet) members, between May and October 2015. RESULTS: Twenty individuals from 13 European countries participated. Ongoing shortages were reported in eight countries routinely using BCG (8/11, 73%). As a consequence of the shortage, BCG was not given as completely unavailable in some countries (2/8, 25%), was given only whenever available (1/8, 13%), or only in certain regions of the country (1/8, 13%). Strategies reported to reduce loss of immunisation were administration to selected high-risk individuals (2/8, 25%), or cohorting vaccinees on specific days to maximise the use of multi-dose vials (3/8, 38%). Authorities in two countries each were considering a change of manufacturer/supplier (2/8, 25%). CONCLUSIONS: The BCG shortage in Europe leads to significant changes in immunisation policies including changes of BCG vaccine strain and manufacturer. In addition, infants and children eligible for immunisation are at risk of not receiving BCG. To ensure necessary BCG immunisations, collaboration between national health agencies and vaccine manufacturers is crucial.
File Format	HTM / HTML
ISSN	14729792
Journal	Tuberculosis
Volume Number	101
e-ISSN	1873281X
Language	English
Publisher	Elsevier
Publisher Date	2016-12-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Pulmonary Medicine
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Immunology Microbiology Microbiology (medical)

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