NDLI: Vaginal infections among pregnant women at Omdurman Maternity Hospital in Khartoum, Sudan.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Abdelaziz, Zeinab A. Ibrahim, Mutasim E. Bilal, Naser E. Hamid, Mohamed E.
Spatial Coverage	Sudan
Description	Country affiliation: Sudan Author Affiliation: Abdelaziz ZA ( Faculty of Medical Laboratory Sciences, Khartoum University, Sudan. nasereldin2001@yahoo.com.)
Abstract	INTRODUCTION: Microbial infections of the vagina in pregnant women are health problems that lead to serious medical complications and consequences. This study aimed to investigate and determine antimicrobial susceptibilities of the causative agents of vaginal infections in pregnant women. METHODOLOGY: A cross-sectional study of pregnant women (n = 200) was conducted between August and December 2008 at Omdurman Maternity Hospital, Khartoum, Sudan. Vaginal and cervical swabs were obtained from each subject and processed for isolation and identification of pathogenic microorganisms using standard methods of wet mount preparation, direct Gram smear, Nugent scoring system, direct immunofluorescence, and cultural techniques. Antimicrobial susceptibility testing of bacterial isolates was performed using standard procedures. Statistical analysis was done using SPSS program version 12.0.1. A p value < 0.05 was considered statistically significant. RESULTS: Of the 200 pregnant women enrolled, BV was detected in 49.8%, followed by Chlamydia trachomatis (31.3%) and Candida albicans (16.6%), with low frequencies of Neisseria gonorrhoeae (1.8%) and Trichomonas vaginalis (0.5%). Higher infection rates were recorded among subjects in the third trimester (71.6%) than in the second trimester of gestation (28.4%). No significant association (p = 0.7) between history of abortions and C. trachomatis infections was found. Gentamicin was the most active agent against Gram-positive and Gram-negative bacteria. Clarythromycin was the most active against Mycoplasma species. CONCLUSIONS: Pregnant women with vaginal complaints revealed various positive microbiology results. Such cases may require specific medication. Routine culture of vaginal and cervical samples should be performed on all pregnant women during prenatal visits.
File Format	HTM / HTML
ISSN	20366590
Issue Number	4
Volume Number	8
Journal	The Journal of Infection in Developing Countries
e-ISSN	19722680
Language	English
Publisher Date	2014-04-15
Publisher Place	Italy
Access Restriction	Subscribed
Subject Keyword	Discipline Communicable Diseases Pregnancy Complications, Infectious Epidemiology Microbiology Pregnancy Complications, Parasitic Parasitology Vaginosis, Bacterial Adolescent Adult Anti-bacterial Agents Pharmacology Candida Albicans Candidiasis Cervix Uteri Coinfection Cross-sectional Studies Escherichia Coli Drug Effects Female Gardnerella Vaginalis Gonorrhea Hospitals, Maternity Humans Microbial Sensitivity Tests Middle Aged Mycoplasma Hominis Neisseria Gonorrhoeae Pregnancy Pregnancy Trimester, Third Prevalence Staphylococcus Aureus Streptococcus Agalactiae Sudan Trichomonas Vaginitis Ureaplasma Urealyticum Vagina Vaginal Diseases Vibrio Young Adult Journal Article
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Virology Parasitology Microbiology

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