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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Bertorello, N. Manicone, R. Galletto, C. Barisone, E. Fagioli, F. |
| Description | Country affiliation: Italy Author Affiliation: Bertorello N ( Division of Pediatric Onco-Hematology and Cell Stem Transplantation, Regina Margherita Children's Hospital, Turin, Italy. nicolettabertorello@libero.it) |
| Abstract | In the present study the authors evaluated therapy-related long-term adverse effects and physical activity in a cohort of long-term survivors of childhood acute lymphoblastic leukemia (ALL), diagnosed in their center between March 1991 and August 2000, treated according to the AIEOP (Associazione Italiana di Ematologia e Oncologia Pediatrica) ALL 91 or 95 study protocol and regularly seen in the authors' long-term follow-up unit. The authors analyzed the long-term sequelae of major body systems in this cohort of subjects and administered an 'ad hoc' questionnaire concerning sport. The authors found that 70 patients out of 102 (68.5%) showed no late effects, 10% presented only instrumental or neuropsychological test abnormalities, and 21.5% had 1 or more clinical late sequelae. None of the evidenced late effects represented a contraindication to do physical activity. Sixty-one percent of survivors do physical activity, most of them regularly. Sixty-one percent of males and 18.5% of females (P < .005) do competitive sport (sports rates are similar to those of the general age-matched population). Nearly all subjects spontaneously choose to do sport and think physical exercise is an important and useful resource for their health. The authors conclude that the more recent therapy regimens for leukemia treatment, excluding bone marrow transplantation, do not seem to cause such late effects as to prevent survivors from doing sport. Therefore, in the care of ALL survivors, physical activity is not only not contraindicated, but should also be promoted as much as possible. The development of specific educational programs is warranted as part of the care of cancer survivors. |
| File Format | HTM / HTML |
| ISSN | 08880018 |
| Issue Number | 5 |
| Volume Number | 28 |
| e-ISSN | 15210669 |
| Journal | Pediatric Hematology and Oncology |
| Language | English |
| Publisher | Taylor & Francis |
| Publisher Date | 2011-08-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Pediatric Discipline Hematology Discipline Oncology Exercise Precursor Cell Lymphoblastic Leukemia-lymphoma Mortality Adolescent Adult Child Child, Preschool Female Humans Infant Male Therapy Sports Survivors Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Hematology Pediatrics, Perinatology and Child Health Oncology |
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