NDLI: Molecular characterization of Canine minute virus associated with neonatal mortality in a litter of Jack Russell terrier dogs.

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Molecular characterization of Canine minute virus associated with neonatal mortality in a litter of Jack Russell terrier dogs.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Decaro, Nicola Amorisco, Francesca Lenoci, Diana Lovero, Angela Colaianni, Maria Loredana Losurdo, Michele Desario, Costantina Martella, Vito Buonavoglia, Canio
Description	Country affiliation: Italy Author Affiliation: Decaro N ( Department of Veterinary Public Health, Faculty of Veterinary Medicine of Bari, Strada per Casamassima Km 3, 70010 Valenzano, Bari, Italy. nicola.decaro@uniba.it)
Abstract	The molecular characterization of a strain of Canine minute virus (CnMV) associated with neonatal death is reported. Three newborn puppies of a litter of Jack Russell terrier dogs died after displaying systemic disease, whereas 2 surviving puppies showed no clinical signs with the exception of transient cardiac abnormalities that were evident by electrocardiography. Necropsy of 1 dead puppy revealed severe lesions in the internal organs. A strain of Canine minute virus was detected in tissue samples collected from the puppy, and virus circulation was demonstrated by molecular or serological testing in the dam, puppies of the same litter, and other puppies in the same kennel. By sequence and phylogenetic analysis of the gene encoding for the VP2 capsid protein, the strain circulating in the kennel was found to be related to recent Asian CnMV isolates. Continuous molecular surveillance for CnMV in kennels, shelters, and rescue centers would expand the knowledge base on the epidemiological and pathogenetic features of CnMV, which has been known for several decades but still poorly understood.
File Format	HTM / HTML
ISSN	10406387
Issue Number	4
Volume Number	24
e-ISSN	19434936
Journal	Journal of Veterinary Diagnostic Investigation
Language	English
Publisher	Sage Publications
Publisher Date	2012-07-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Veterinary Medicine Bocavirus Isolation & Purification Dog Diseases Virology Parvoviridae Infections Veterinary Amino Acid Sequence Animals Animals, Newborn Antibodies, Viral Blood Base Sequence Genetics Capsid Proteins Chemistry Dna, Viral Dogs Fatal Outcome Female Male Molecular Sequence Data Polymerase Chain Reaction Pregnancy Sequence Alignment Case Reports Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Case study Article
Subject	Veterinary

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Molecular characterization of Canine minute virus associated with neonatal mortality in a litter of Jack Russell terrier dogs.

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