NDLI: Modified titanium surfaces alter osteogenic differentiation: a comparative microarray-based analysis of human mesenchymal cell response to commercial titanium surfaces.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Mamalis, Anastasios Silvestros, Spyridon
Abstract	The differential effects of dual-acid etched (Osseotite), hydroxyapatite coated (HA) and sand-blasted/acid-etched (SLA) titanium surfaces on human bone marrow-derived mesenchymal cells (hMSCs) were investigated. Proliferation was significantly promoted on the SLA surfaces. 16 genes were significantly upregulated when hMSCs were cultured on the Osseotite and the HA surfaces and 15 genes on the SLA surfaces. Upregulated genes control cell differentiation, signal transduction, cell cycle regulation, angiogenesis, cell adhesion, and extracellular matrix and bone formation.
File Format	HTM / HTML
ISSN	01606972
Issue Number	5
Volume Number	39
e-ISSN	15481336
Journal	Journal of Oral Implantology
Language	English
Publisher	American Association of Implant Dentistry
Publisher Date	2013-10-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Dentistry Discipline General Surgery Cell Adhesion Dental Implants Mesenchymal Stromal Cells Osteogenesis Genetics Titanium Air Abrasion, Dental Analysis Of Variance Bone Marrow Cells Cell Differentiation Cell Proliferation Cells, Cultured Coated Materials, Biocompatible Durapatite Extracellular Matrix Physiology Gene Expression Profiling Humans Cytology Oligonucleotide Array Sequence Analysis Osteoblasts Regression Analysis Surface Properties Comparative Study Journal Article
Content Type	Text
Resource Type	Article
Subject	Oral Surgery

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