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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Bennewitz, J. Meuwissen, T. H. E. |
| Description | Country affiliation: Germany Author Affiliation: Bennewitz J ( Institute of Animal Husbandry and Breeding, University of Hohenheim, D-70599 Stuttgart, Germany. j.bennewitz@uni-hohenheim.de) |
| Abstract | The present study used published quantitative trait loci (QTL) mapping data from three F2 crosses in pigs for 34 meat quality and carcass traits to derive the distribution of additive QTL effects as well as dominance coefficients. Dominance coefficients were calculated as the observed QTL dominance deviation divided by the absolute value of the observed QTL additive effect. The error variance of this ratio was approximated using the delta method. Mixtures of normal distributions (mixtures of normals) were fitted to the dominance coefficient using a modified EM-algorithm that considered the heterogeneous error variances of the data points. The results suggested clearly to fit one component which means that the dominance coefficients are normally distributed with an estimated mean (standard deviation) of 0.193 (0.312). For the additive effects mixtures of normals and a truncated exponential distribution were fitted. Two components were fitted by the mixtures of normals. The mixtures of normals did not predict enough QTL with small effects compared to the exponential distribution and to literature reports. The estimated rate parameter of the exponential distribution was 5.81 resulting in a mean effect of 0.172. |
| File Format | HTM / HTML |
| ISSN | 09312668 |
| Issue Number | 3 |
| Volume Number | 127 |
| e-ISSN | 14390388 |
| Journal | Journal of Animal Breeding and Genetics |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2010-06-01 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Genetics Discipline Reproductive Medicine Discipline Veterinary Medicine Discipline Zoology Breeding Methods Inheritance Patterns Genetics Meat Models, Genetic Quantitative Trait Loci Sus Scrofa Algorithms Animals Body Composition Crosses, Genetic Likelihood Functions Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Animal Science and Zoology Food Animals |
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