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Development of a new strategy of visual field testing for macular dysfunction in patients with open angle glaucoma.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Omodaka, Kazuko Kunimatsu-Sanuki, Shiho Morin, Ryu Tsuda, Satoru Yokoyama, Yu Takahashi, Hidetoshi Maruyama, Kazuichi Kunikata, Hiroshi Nakazawa, Toru
Description	Country affiliation: Japan Author Affiliation: Omodaka K ( Department of Ophthalmology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.)
Abstract	PURPOSE: To explore methods of automated visual field (VF) examination for the assessment of macular function. METHOD: We used a VF examination (AP-7000 automatic perimeter, Kowa, Japan) to examine macular function in 53 eyes from 29 patients with open angle glaucoma. We measured the mean total deviation (c-MD) of 16 points in the central VF located in a 2-degree-interval 4 × 4 array with various stimulus sizes (Goldmann sizes III, II, and I). The retinal nerve fiber layer (RNFL) thickness, ganglion cell complex (GCC), and ganglion cell layer plus inner plexiform layer (GCL + IPL) were measured with the 3D OCT-2000 System (Topcon, Japan). The c-MDs of various stimulus sizes were compared with the OCT parameters using the Spearman rank correlation. RESULTS: The average examination time was 93.5 ± 23.5 s and the c-MD values were -11.8 ± 8.2 (stimulus size III), -11.9 ± 9.5 (stimulus size II), and -12.3 ± 9.6 dB (stimulus size I). The c-MD (stimulus size III) and averaged total deviations of the Humphrey Field Analysis 10-2 program were significantly correlated (ρ = 0.91). The C-MD values for stimulus size III were significantly correlated with the OCT parameters (RNFL: ρ = 0.59; GCC: ρ = 0.65; and GCL + IPL: ρ = 0.64). The correlation coefficient between the c-MD and the GCC was better for stimulus sizes II and I (ρ = 0.69) than for stimulus size III (ρ = 0.65). CONCLUSION: The C-MD values for the 16 measured central VF points were significantly correlated with macular structure, and the smaller stimulus sizes of the automated VF test had a higher correlation coefficient of within 8°.
File Format	HTM / HTML
ISSN	00215155
Issue Number	5
Volume Number	57
e-ISSN	16132246
Journal	Japanese Journal of Ophthalmology
Language	English
Publisher	Springer
Publisher Date	2013-09-01
Publisher Place	Japan
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Ophthalmology Glaucoma, Open-angle Diagnosis Nerve Fibers Pathology Retinal Diseases Retinal Ganglion Cells Vision Disorders Visual Fields Disease Progression Female Humans Male Middle Aged Tomography, Optical Coherence Visual Field Tests Journal Article
Content Type	Text
Resource Type	Article
Subject	Ophthalmology

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