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The effects of undifferentiated spondyloarthropathy on left ventricular systolic and diastolic function.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Albayrak, Neslihan Bayram, Nihal A. Erten, Sukran Sari, Cenk Keles, Telat Durmaz, Tahir Bastug, Serdal Bozkurt, Engin
Description	Country affiliation: Turkey Author Affiliation: Albayrak N ( Department of Cardiology, Ataturk Education and Research Hospital, Ankara, Turkey.)
Abstract	BACKGROUND: Recent studies report that cardiovascular mortality is more common in patients with spondyloarthropathy (SpA) compared with the normal population. In this study, we aimed to determine left ventricular systolic and diastolic functions using tissue Doppler echocardiography (TDE) in addition to conventional methods in undifferentiated SpA (uSpA) patients. METHODS: A total of 45 patients and 44 age and sex matched healthy controls participated in the present study. Left ventricular systolic and diastolic functions were assessed with two dimensional (2D) echocardiography, M-mode echocardiography, pulsed-wave (PW) echocardiography and tissue Doppler echocardiography. The peak systolic velocity (Sm), early diastolic myocardial peak velocity (Em), and late diastolic myocardial peak velocity (Am), myocardial isovolumetric contraction time (IVCTm), myocardial ejection time (ETm), myocardial isovolumetric relaxation time (IVRTm) and myocardial performance index (MPI) were measured at septal and lateral mitral annulus. RESULTS: Left ventricular diastolic inflow velocities showed that isovolumetric relaxation time (IVRT) and deceleration time (DT) were significantly longer in the uSpA group. Left ventricular lateral wall PW tissue Doppler echocardiography showed that Em was significantly lower in uSpA group. Septal PW tissue Doppler echocardiography showed that Em was lower and IVRT was longer in the uSpA group compared with healthy controls. CONCLUSION: In this study we determined that left ventricular systolic function is preserved in patients with uSpA. Although frequency of diastolic dysfunction was similar in both groups, deterioration of some diastolic parameters in the uSpA group might be considered for possible cardiac involvement in patients with uSpA.
File Format	HTM / HTML
ISSN	17561841
Issue Number	2
Volume Number	16
e-ISSN	1756185X
Journal	International Journal of Rheumatic Diseases
Language	English
Publisher	Wiley
Publisher Date	2013-04-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Rheumatology Diastole Spondylarthropathies Complications Systole Ventricular Dysfunction, Left Etiology Ventricular Function, Left Adult Case-control Studies Chi-square Distribution Cross-sectional Studies Echocardiography, Doppler, Pulsed Female Humans Male Middle Aged Predictive Value Of Tests Diagnosis Stroke Volume Physiopathology Journal Article
Content Type	Text
Resource Type	Article
Subject	Rheumatology

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