NDLI: Maternal cardiac function in preeclampsia.

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Maternal cardiac function in preeclampsia.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Melchiorre, Karen Thilaganathan, Basky
Description	Country affiliation: United kingdom Author Affiliation: Melchiorre K ( Department of Obstetrics and Gynecology, Fetal Maternal Medicine Unit, St Georges Hospital, University of London, London, UK.)
Abstract	PURPOSE OF REVIEW: Acute cardiovascular complications affect 6% of severe preeclampsia and epidemiological studies demonstrate a strong association between preeclampsia and subsequent cardiovascular morbidity and mortality. This data suggests that not only can preeclampsia acutely impair cardiac function, but also it has the potential to provoke myocardial ischaemia and affect long-term cardiovascular health. This review highlights the recent insights on cardiovascular impairment in preeclampsia and postpartum. RECENT FINDINGS: Recent studies on preeclampsia have used newer echocardiographic indices that are more sensitive at detecting asymptomatic myocardial damage, better correlated to invasive indices of myocardial function and are predictive for subsequent cardiovascular morbidity. Current findings indicate an unexpectedly high prevalence of cardiac impairment in preeclampsia and postpartum. These findings have important implications for the long-term cardiovascular health of women whose pregnancies were complicated by preeclampsia. SUMMARY: Preeclampsia is associated with stage B heart failure (asymptomatic left ventricular dysfunction/hypertrophy), a high prevalence of essential hypertension and an increased cardiovascular risk status within few years postpartum. These findings are more prevalent with early onset/preterm preeclampsia. These cardiovascular findings are consistent with epidemiological studies showing a 'dose-dependent' relationship between preeclampsia and long-term cardiovascular morbidity and mortality. There is increasing evidence supporting the concept that a history of early onset/preterm preeclampsia should be taken into account to identify women at high cardiovascular risk even in the absence of other concomitant risk factors.
File Format	HTM / HTML
ISSN	1040872X
Issue Number	6
Volume Number	23
e-ISSN	1473656X
Journal	Current Opinion in Obstetrics and Gynecology
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2011-12-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Obstetrics Discipline Gynecology Hypertrophy, Left Ventricular Physiopathology Pre-eclampsia Pregnancy Complications, Cardiovascular Ventricular Dysfunction, Left Cardiovascular Diseases Echocardiography, Doppler Female Humans Postpartum Period Pregnancy Etiology Risk Factors Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Obstetrics and Gynecology

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