NDLI: Exercise training increases hepatic endoplasmic reticulum (er) stress protein expression in MTP-inhibited high-fat fed rats.

Please wait, while we are loading the content...

Year: 2017 Volume: 35

Year: 2016 Volume: 34

Year: 2015 Volume: 33

Year: 2014 Volume: 32

Year: 2013 Volume: 31

Year: 2012 Volume: 30

Year: 2011 Volume: 29

Year: 2010 Volume: 28

Year: 2010 Volume: 28 Issue: 8

Year: 2010 Volume: 28 Issue: 7

Year: 2010 Volume: 28 Issue: 6

Year: 2010 Volume: 28 Issue: 5

Year: 2010 Volume: 28 Issue: 4

Year: 2010 Volume: 28 Issue: 3

Preventive role of PD-1 on MPTP-induced dopamine depletion in mice.

The pharmacological role of nucleotidases in snake venoms.

Erythropoietin induces nuclear translocation of Nrf2 and heme oxygenase-1 expression in SH-SY5Y cells.

Pluripotent plasticity of stem cells and liver repopulation.

Vascular redox imbalance in rats submitted to chronic exercise.

New volatile anesthetic, desflurane, reduces vitamin E level in blood of operative patients via oxidative stress.

Proton leak modulation in testicular mitochondria affects reactive oxygen species production and lipid peroxidation.

Exercise training increases hepatic endoplasmic reticulum (er) stress protein expression in MTP-inhibited high-fat fed rats.

Experimental chronic low-frequency resistance training produces skeletal muscle hypertrophy in the absence of muscle damage and metabolic stress markers.

Role of mitogen-activated protein kinase in Zn-BC-AM PDT-induced apoptosis in nasopharyngeal carcinoma cells

Year: 2010 Volume: 28 Issue: 2

Year: 2010 Volume: 28 Issue: 1

Year: 2009 Volume: 27

Year: 2008 Volume: 26

Exercise training increases hepatic endoplasmic reticulum (er) stress protein expression in MTP-inhibited high-fat fed rats.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Chapados, Natalie Ann Lavoie, Jean-Marc
Description	Country affiliation: Canada Author Affiliation: Chapados NA ( Department of Kinesiology, University of Montreal, Montréal, Québec, Canada. n.chapados@gmail.com)
Abstract	The purpose of the study was: (1) to determine the effects of microsomal triglyceride transfer protein (MTP) inhibition on endoplasmic reticulum (ER) stress in liver, and (2) to determine if this response is altered in exercise-trained rats. Female Sprague-Dawley rats (6 weeks) fed either a standard (SD) or a high-saturated fat (HF; 43% as energy) diet were trained (Tr) or kept sedentary (Sed) for 6 week. Exercise training consisted of continuous running on a motor-driven rodent treadmill 5 times/week. Ten days before the end of these interventions, rats were administrated (ip) daily a MTP inhibitor (MTPX) or a placebo (P). MTPX injection resulted in a large (p < 0.01) liver triacylglycerol (TAG) accumulation in SD and HF-fed rats (approximately 200 mg g(-1)), irrespective of the training status, while plasma TAG levels were largely (approximately 80%) decreased (p < 0.01). MTPX injection in HF but not in SD-fed animals resulted in an increase in BiP/GRP78, ATF6, PERK, and XBP-1 mRNA levels, (p < 0.01) indicating an increase in the unfolding protein response (UPR) to ER stress. Interestingly, exercise training in rats fed the HF diet resulted in a further increase in BiP/GRP78 and XBP-1 mRNA levels in MTPX animals (p < 0.01). It is concluded that: (1) ER stress induced by MTPX occurs only in HF-fed rats despite the fact that liver TAG levels were largely increased in both dietary models; (2) the increase in gene expression of UPR markers with training may constitute a protective mechanism against ER stress in liver.
File Format	HTM / HTML
ISSN	02636484
Issue Number	3
Volume Number	28
e-ISSN	10990844
Journal	Cell Biochemistry and Function
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2010-04-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Cell Biology Discipline Biochemistry Carrier Proteins Antagonists & Inhibitors Dietary Fats Endoplasmic Reticulum Metabolism Heat-shock Proteins Liver Physical Conditioning, Animal Physiology Animals Biological Markers Body Composition Diet Energy Metabolism Female Gene Expression Genetics Humans Cytology Placebos Rats Rats, Sprague-dawley Triglycerides Blood Unfolded Protein Response Journal Article
Content Type	Text
Resource Type	Article
Subject	Cell Biology Medicine Biochemistry Clinical Biochemistry

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in