NDLI: Reference ranges of lymphocyte subsets in healthy Qatari adults.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Al-Thani, Asma Hamdi, Wedad S. Al-Marwani, Asma Alnaqdy, Adel Sharafeldin, Hend
Description	Author Affiliation: Al-Marwani A ( 2Hematology Department, Hamad General Hospital, Hamad Medical Corporation, Doha.); Alnaqdy A ( 3Immunolgy Department, Hamad General Hospital, Hamad Medical Corporation, Doha.); Sharafeldin H ( 4Laboratory Department, Qatar Armed Forces Medical Services, Doha, Qatar.)
Abstract	AIM: Determine reference ranges of lymphocyte subsets in healthy Qatari adults. PATIENTS & METHODS: Blood samples (n = 150) were investigated using four colors flow cytometery. RESULTS: The mean percentage and absolute values of the lymphocyte subsets were: CD3: 73.6 ± 6.1%; 2,072 ± 644 cells/µl; CD4: 41.1 ± 7.9%; 1,167 ± 396 cells/µl; CD8: 33.8 ± 7.1%; 967 ± 364 cells/µl; B cells (CD19(+)): 11.3 ± 3.9%; 318 ± 144 cells/µl and natural killer (NK) cells (CD16/56(+)): 16.5 ± 6.3%, 440 ± 401 cells/µl, respectively. The CD4/CD8 ratio was 1.3 ± 0.5. The ratio, CD3(+) and CD4(+) percentage and CD4(+) cell counts were significantly higher in females; CD8(+) and NK cell count and CD8(+) percentage were significantly higher in males. The impact of age was less certain. CONCLUSION: The reference values of lymphocyte subsets appear to be specific to this population, demonstrating the importance of establishing local reference ranges.
File Format	HTM / HTML
ISSN	17520363
Issue Number	5
Volume Number	9
e-ISSN	17520371
Journal	Biomarkers in Medicine
Language	English
Publisher	Future Science Group
Publisher Date	2015-01-01
Publisher Place	Great Britain (UK)
Access Restriction	Subscribed
Subject Keyword	Discipline Biochemistry Lymphocyte Subsets Cytology Adolescent Adult Aged Aged, 80 And Over Cd4-cd8 Ratio Female Flow Cytometry Healthy Volunteers Humans Metabolism Male Middle Aged Reference Values Young Adult Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Biochemistry (medical) Drug Discovery Clinical Biochemistry

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