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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Emad, Raddaoui Maha, Arafah Kfoury, Hala K. Al-Sheikh, Abdul Malik Zaidi, Shaesta N. |
| Description | Country affiliation: Saudi Arabia Author Affiliation: Emad R ( Department of Histopathology, King Saud University, King Khalid University Hospital, Riyadh, Saudi Arabia. eraddaoui@yahoo.com) |
| Abstract | The macrofollicular variant of papillary thyroid carcinoma (MFPTC) is a well-established entity with characteristic large follicles containing pale colloid and lined by cells with nuclear features of papillary thyroid carcinoma (PTC). In this study, we present three cases of MFPTC, along with a brief review of the literature. For all three of our cases, the histology of the resected specimen showed predominantly macrofollicular structures lined by cells with nuclear characteristics of PTC. Immunohistochemically, the three cases show positivity for galactin-3, cytokeratin-19, and HBME-1. These cases will help us in understanding the distinction from other benign and malignant follicular lesions of the thyroid, which is of utmost importance. The key to diagnosis is a high-power examination of any macrofollicular lesion of the thyroid. |
| File Format | HTM / HTML |
| ISSN | 02564947 |
| e-ISSN | 09754466 |
| DOI | 10.4103/0256-4947.87104 |
| Journal | Annals of Saudi Medicine |
| Issue Number | 6 |
| Volume Number | 31 |
| Language | English |
| Publisher | King Faisal Specialist Hospital and Research Centre |
| Publisher Date | 2011-11-01 |
| Publisher Place | Saudi Arabia |
| Access Restriction | Open |
| Subject Keyword | Discipline Medicine Carcinoma Thyroid Gland Pathology Thyroid Neoplasms Biopsy, Fine-needle Diagnosis Metabolism Diagnosis, Differential Immunohistochemistry Prognosis |
| Content Type | Text |
| Resource Type | Case study Article |
| Subject | Medicine |
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