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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Abdalla, Mohgah Sh Saad-Hussein, Amal Ibrahim, Khadiga Salah El-mezayen, Hatem A. Osman, Nehal F. A. |
| Description | Country affiliation: Egypt Author Affiliation: Abdalla MSh ( Chemistry Department, Helwan University, Giza, Egypt.); Saad-Hussein A ( Department of Environmental and Occupational Medicine, National Research Centre, Giza, Egypt.); Ibrahim KS ( Department of Environmental and Occupational Medicine, National Research Centre, Giza, Egypt khadigasalah@yahoo.com.); El-mezayen HA ( Chemistry Department, Helwan University, Giza, Egypt.); Osman NF ( Chemistry Department, Helwan University, Giza, Egypt.) |
| Abstract | The present study was conducted on 80 pesticide male sprayers (42 nonsmokers and 38 smokers). Our aim was to estimate the smoking effects on blood lipids and oxidant/antioxidant status in pesticide sprayers. Results revealed that cholesterol, low-density lipoprotein (LDL) and glutathion peroxidase (GPx) enzyme were significantly higher in the 38 smoker sprayers than in the 42 nonsmoker sprayers. Cholesterol and LDL were correlated with smoking index and high-density lipoprotein (HDL), superoxide dismutase (SOD) enzyme and zinc (Zn) were inversely correlated with duration of pesticides' exposure. In nonsmokers, LDL and cholesterol were negatively correlated with SOD and correlated with malondialdehyde (MDA), and cholesterol was negatively correlated with Zn. HDL was negatively correlated with MDA in all the sprayers, but was correlated with GPx in smokers and with Zn in nonsmokers. In smokers, LDL was negatively correlated with GPx, HDL was negatively correlated with MDA and triglycerides and very-low-density lipoprotein were negatively correlated with Zn. MDA was negatively correlated with SOD, GPx and Zn. Smoking and pesticide exposure could be responsible for hyperlipidemia and oxidative stress. Therefore, improvement in the antioxidant status is mandatory for pesticide sprayers especially the ones who smoke. |
| File Format | HTM / HTML |
| ISSN | 07482337 |
| Issue Number | 2 |
| Volume Number | 31 |
| e-ISSN | 14770393 |
| Journal | Toxicology and Industrial Health |
| Language | English |
| Publisher | Sage Publications |
| Publisher Date | 2015-02-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Occupational Medicine Discipline Toxicology Agriculture Statistics & Numerical Data Antioxidants Analysis Occupational Exposure Oxidative Stress Drug Effects Pesticides Adverse Effects Smoking Epidemiology Adult Aged Case-control Studies Humans Lipids Blood Male Middle Aged Oxidoreductases Young Adult Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health Toxicology |
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