NDLI: Quantitative Determination of Plasma and Urine Paraquat Concentrations using Spectroscopic Method

Please wait, while we are loading the content...

Year: 2011 Volume: 31

Year: 2010 Volume: 30

Year: 2009 Volume: 29

Year: 2008 Volume: 28

Year: 2007 Volume: 27

Year: 2006 Volume: 26

Year: 2005 Volume: 25

Year: 2004 Volume: 24

Year: 2003 Volume: 23

Year: 2002 Volume: 22

Year: 2002 Volume: 22 Issue: 6

Year: 2002 Volume: 22 Issue: 3

Cytogenetic Analysis in 651 Cases of Amniocentesis

Tumor Necrosis Factor Alpha Gene Polymorphisms in Schizophrenia

Clinical Evaluation of HBeAg Quantitation Using Enzyme Immunoassay in the Follow-Up of Patients with Chronic Hepatitis B

Evaluation of a Spectrophotometric Broth Microdilution Method for Determining Fluconazole Susceptibility of Candida albicans: Influence of RPMI and RPMI-2% Glucose on the Selection of Endpoint Criteria

Molecular Epidemiologic Analysis of vanA-Containing Vancomycin-Resistant Enterococci

Combination Effects of Various Beta-Lactam Antibiotics with Vancomycin or Teicoplanin against Staphylococcus aureus with Reduced Susceptibility to Vancomycin

Report of 3 Cases of Chronic Myelogenous Leukemia with Thrombocythemic Onset

Basic Evaluation of Roche OMNI 9 Blood Gas Analyzer

Assessment of the Diagnostic Utility of Methylmalonic Acid in Megaloblastic Anemia due to Vitamin B12 Deficiency

Quantitative Determination of Plasma and Urine Paraquat Concentrations using Spectroscopic Method

Hyperhomocysteinemia as a Risk Factor for Coronary Artery Disease

Quantitative Determination of Plasma and Urine Paraquat Concentrations using Spectroscopic Method

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Park, J. W. Kim, J. K. Rheem, I. S. Kim, G. T. Yoon, S. C. Jang, W. C. Kim, J. S. Kim, J. W.
Description	Responsible library: WPRO
Abstract	BACKGROUND: It is well known that plasma paraquat concentration is one of the most important prognostic indicators for paraquat poisoning. Quantitative analyses of paraquat, however, are not generally used in clinical laboratories. In this work, we evaluated the second-derivative spectroscop-ic method for quantitation of paraquat in plasma and urine, and investigated the clinical significance in patients with paraquat poisoning. METHODS: Linearity, precision, interferences, and comparison with high-performance liquid chro-matography (HPLC) were evaluated in 20 paraquat-poisoning cases using the UV-160 A recording spectrophotometer. The relationship of plasma and urine paraquat concentrations with the clinical outcomes was also studied. RESULTS: The within-run and between-day coefficients of variation (CV) for groups of low and high levels were less than 5%. The derivative amplitude was linearly related to paraquat concentra-tion through the range from 0.5 to 10 ng/mL. The correlation coefficient (r) between spectrophotom-etry and HPLC was 0.992. The accuracy for predicting the outcome for patients based on plasma paraquat concentration was 84.6%. The urine paraquat levels on admission were more than 10 ng/ mL in all of the 9 non-survivors group and in 5 out of 11 of the survivors group. The eliminating rates for plasma and urine paraquat concentrations by extracorporeal procedures were not statistically different between the two groups. CONCLUSIONS: Second-derivative spectroscopic methods for quantitation of paraquat showed an acceptable performance and suitable procedure for clinical laboratory use and it was thought to beseful in assessing the severity and in predicting the prognosis for paraquat poisoning.
File Format	HTM / HTML
ISSN	22343806
e-ISSN	22343814
Journal	The Korean Journal of Laboratory Medicine
Issue Number	3
Volume Number	22
Language	Korean
Publisher	Korean Society for Laboratory Medicine
Publisher Date	2002-01-01
Publisher Place	Korea (South)
Access Restriction	Open
Subject Keyword	Discipline Medical Laboratory Technology Paraquat Plasma Attention In Urine
Content Type	Text
Resource Type	Article
Subject	Biochemistry (medical) Clinical Biochemistry

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in