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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Coëtmeur, D. Leveiller, G. Frappat, V. Martin, M. Peureux, M. Dehette, S. Carbonnelle, M. Dayen, C. Debieuvre, D. Grivaux, M. |
| Description | Author Affiliation: Coëtmeur D ( Service de pneumologie et d'oncologie thoracique, hôpital Yves-Le-Foll, 10, rue Marcel-Proust, 22027 Saint-Brieuc cedex 1, France. Electronic address: daniel.coetmeur@ch-stbrieuc.fr.); Leveiller G ( Service de pneumologie et d'oncologie thoracique, hôpital Yves-Le-Foll, 10, rue Marcel-Proust, 22027 Saint-Brieuc cedex 1, France.); Frappat V ( Service de pneumologie, centre hospitalier Métropole Savoie, 73000 Chambéry, France.); Martin M ( Service de pneumologie, centre hospitalier d'Angoulême, 16959 Angoulême, France.); Peureux M ( Service de pneumologie, hôpital Jacques-Monod, centre hospitalier Le Havre, 76290 Montivilliers, France.); Dehette S ( Service de pneumologie, centre hospitalier Compiègne-Noyon, 60200 Compiègne, France.); Carbonnelle M ( Service de pneumologie, centre hospitalier Auban-Moët, 51205 Epernay, France.); Dayen C ( Service de pneumologie, centre hospitalier de Saint-Quentin, 02321 Saint-Quentin cedex, France.); Debieuvre D ( Service de pneumologie, hôpital Émile-Muller, 68070 Mulhouse, France.); Grivaux M ( Service de pneumologie, centre hospitalier de Meaux, 77104 Meaux cedex, France.) |
| Abstract | INTRODUCTION: The Collège des Pneumologues des Hôpitaux Généraux has performed a prospective multicentre epidemiological study which aims to describe the baseline characteristics of all new cases of primary lung cancer histologically or cytologically diagnosed in 2010 and followed-up in the respiratory department of general hospitals. The present publication compares the characteristics of these presentations according to their smoking history. METHODS: Seven thousand and fifty-one adult patients were included from 104 respiratory departments. A standardized form was completed at diagnosis and a steering committee checked the completeness of inclusion. RESULTS: Only 10.9% of patients were never-smokers and 89.1% ever-smokers (i.e., current or former smokers). Respectively, 3.7%, 10.7% and 85.6% of ever-smokers consumed/had consumed 1-10, 11-20, and >20 pack-years. Mean smoking duration was 37.5 years. Former smokers had stopped smoking on average 14.8 years previously. Only 20.7% of never-smokers reported that they had been exposed to tobacco smoke passively. At diagnosis, statistically significant differences were found between never- and ever-smokers (P<0.0001) for sex (women: 60.8% vs 18.8%), age (mean: 70.7 years vs 64.9 years), stage (IV: 70.8% vs 58.7%), histology (adenocarcinoma: 68.5% vs 42.6%), EGFR mutation exploration (51.4% vs 28.0%) and positivity (37.0% vs 4.6%). Differences between never- and ever-smokers rose with increasing tobacco consumption. CONCLUSIONS: This study confirms that differences exist between never- and ever-smoker patients presenting with primary lung cancer and shows the impact of the level of tobacco consumption, in particular on histology. |
| File Format | HTM / HTML |
| ISSN | 07618425 |
| Issue Number | 7 |
| Journal | Revue des Maladies Respiratoires |
| Volume Number | 33 |
| e-ISSN | 17762588 |
| Language | French |
| Publisher | Elsevier |
| Publisher Date | 2016-09-01 |
| Publisher Place | France |
| Access Restriction | Subscribed |
| Subject Keyword | Discipline Pulmonary Medicine |
| Alternative Title | Relationship between primary lung cancer and tobacco consumption. Results of the KBP-2010-CPHG study by the French College of General Hospital Respiratory Physicians |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pulmonary and Respiratory Medicine |
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