NDLI: Pragmatic Language Features of Mothers With the FMR1 Premutation Are Associated With the Language Outcomes of Adolescents and Young Adults With Fragile X Syndrome.

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Pragmatic Language Features of Mothers With the FMR1 Premutation Are Associated With the Language Outcomes of Adolescents and Young Adults With Fragile X Syndrome.

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Pragmatic Language Features of Mothers With the FMR1 Premutation Are Associated With the Language Outcomes of Adolescents and Young Adults With Fragile X Syndrome.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Klusek, Jessica McGrath, Sara E. Abbeduto, Leonard Roberts, Jane E.
Abstract	PURPOSE: Pragmatic language difficulties have been documented as part of the FMR1 premutation phenotype, yet the interplay between these features in mothers and the language outcomes of their children with fragile X syndrome is unknown. This study aimed to determine whether pragmatic language difficulties in mothers with the FMR1 premutation are related to the language development of their children. METHOD: Twenty-seven mothers with the FMR1 premutation and their adolescent/young adult sons with fragile X syndrome participated. Maternal pragmatic language violations were rated from conversational samples using the Pragmatic Rating Scale (Landa et al., 1992). Children completed standardized assessments of vocabulary, syntax, and reading. RESULTS: Maternal pragmatic language difficulties were significantly associated with poorer child receptive vocabulary and expressive syntax skills, with medium effect sizes. CONCLUSIONS: This work contributes to knowledge of the FMR1 premutation phenotype and its consequences at the family level, with the goal of identifying modifiable aspects of the child's language-learning environment that may promote the selection of treatments targeting the specific needs of families affected by fragile X. Findings contribute to our understanding of the multifaceted environment in which children with fragile X syndrome learn language and highlight the importance of family-centered intervention practices for this group.
File Format	HTM / HTML
ISSN	10924388
e-ISSN	15589102
DOI	10.1044/2015_JSLHR-L-15-0102
Journal	Journal of Speech Language and Hearing Research
Issue Number	1
Volume Number	59
Language	English
Publisher	American Speech-Language-Hearing Association
Publisher Date	2016-02-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Audiology
Content Type	Text
Resource Type	Article
Subject	Medicine Speech and Hearing Linguistics and Language

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