NDLI: Suicidal thoughts are associated with platelet counts in adolescent inpatients.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Ragolsky, Micha Shimon, Hady Shalev, Hadar Weizman, Abraham Rubin, Eitan
Description	Country affiliation: Israel Author Affiliation: Ragolsky M ( The Beer-Sheva Mental Health Center, Beer-Sheva, Israel. ragolsky@bgu.ac.il)
Abstract	OBJECTIVE: Platelets (PLT), which serve as the primary hemostatic indicator, can be used as a peripheral model for studying monoamine turnover in the brain. Therefore, they are attractive targets as circulatory biomarkers for the detection of psychiatric disorders. However, PLT counts have not been utilized as a peripheral biomarker of psychopathology. METHODS: This study was a retrospective analysis of PLT counts upon admission of 108drug-naïve adolescents hospitalized in an inpatient psychiatric department. PLT counts of patients with suicidal ideation (SI) were compared with those of nonsuicidal in patients (NSI) and those of 77 healthy adolescents, serving as a control group. The patients' disorders were diagnosed and classified by one of four American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM IV) diagnoses, that is, unipolar depression, bipolar depression, schizophrenia, and a pooled group of conduct and borderline personality disorders. RESULTS: Significantly higher PLT counts were observed in SI patients, as compared with NSI patients (300,200±53.3/mL vs. 253,900±53.2/mL, respectively; p=0.0001). A significant difference in PLT counts in SI patients, relative to the control group, was also noted (300,200±53.3/mL vs. 254,000±52/mL, respectively; p=<10(-26)). Finally, a significant difference in PLT counts was observed between conduct/borderline personality disorders patient with and without suicidal ideation (292,000±55/mL vs. 246,000±64/mL, respectively; p=0.001). CONCLUSIONS: PLT counts are higher in suicidal hospitalized adolescents than in nonsuicidal inpatients, as well as than in controls.
File Format	HTM / HTML
ISSN	10445463
Issue Number	1
Volume Number	23
e-ISSN	15578992
Journal	Journal of Child and Adolescent Psychopharmacology
Language	English
Publisher	Mary Ann Liebert
Publisher Date	2013-02-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Pediatrics Adolescent Behavior Psychology Blood Platelets Cytology Mental Disorders Blood Suicidal Ideation Adolescent Physiology Case-control Studies Child Diagnostic And Statistical Manual Of Mental Disorders Female Humans Inpatients Male Platelet Count Retrospective Studies Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Pharmacology (medical) Pediatrics, Perinatology and Child Health Psychiatry and Mental Health

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in