NDLI: Electrophysical therapy for managing diabetic foot ulcers: a systematic review.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Kwan, Rachel L-C Cheing, Gladys L-Y Vong, Sinfia K-S Lo, Sing K.
Description	Country affiliation: China Author Affiliation: Kwan RL ( Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China.)
Abstract	To systematically assess published reports on the efficacy of electrophysical therapy in the treatment of diabetic foot ulcers, including electrical stimulation, low-level laser therapy, therapeutic ultrasound and electromagnetic therapy. Databases searched included MEDLINE, CINAHL, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL) from 1966 to 2011. Studies reviewed included only randomised controlled trials (RCTs) on treatment with electrophysical modalities compared with sham, conventional treatment or other electrophysical modalities. Information extracted were objective measures of healing and data useful for the calculation of effect size. Eight RCTs were eventually included in the critical appraisal, with a combined total of 325 participants. Five studies were conducted on electrical stimulation, two on phototherapy and one on ultrasound. All studies reported that the experimental group was significantly more favourable than the control or sham group. The pooled estimate of the number of healed ulcers of the three studies on electrical stimulation compared to the control or sham electrical stimulation showed statistical significance [mean difference of 2·8 (95% CI = 1·5-5·5, P = 0·002] in favour of electrical stimulation. The results indicated potential benefit of using electrophysical therapy for managing diabetic foot ulcers. However, due to the small number of trials ever conducted, the possibility of any harmful effects cannot be ruled out, and high-quality trials with larger sample sizes are warranted.
File Format	HTM / HTML
ISSN	17424801
Issue Number	2
Volume Number	10
e-ISSN	1742481X
Journal	International Wound Journal
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2013-04-01
Publisher Place	Great Britain (UK)
Access Restriction	Subscribed
Subject Keyword	Discipline Traumatology Diabetic Foot Rehabilitation Adult Aged Aged, 80 And Over Electric Stimulation Therapy Electromagnetic Phenomena Female Humans Laser Therapy, Low-level Male Middle Aged Randomized Controlled Trials As Topic Treatment Outcome Ultrasonic Therapy Wound Healing Journal Article Research Support, Non-u.s. Gov't Review
Content Type	Text
Resource Type	Article
Subject	Surgery Dermatology

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