NDLI: Clinical Presentation, Management and Outcome of Japanese Patients With Acute Myocardial Infarction in the Troponin Era - Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET)

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Ishihara, Masaharu Fujino, Masashi Ogawa, Hisao Yasuda, Satoshi Noguchi, Teruo Nakao, Koichi Ozaki, Yukio Kimura, Kazuo Suwa, Satoru Fujimoto, Kazuteru Nakama, Yasuharu Morita, Takashi Shimizu, Wataru Saito, Yoshihiko Tsujita, Kennichi Nishimura, Kunihiko Miyamoto, Yoshihiro
Spatial Coverage	Japan
Description	Author Affiliation: Ishihara M ( Division of Coronary Artery Disease, Department of Internal Medicine, Hyogo College of Medicine.)
Abstract	BACKGROUND: New criteria for diagnosis of acute myocardial infarction (AMI) were proposed in 2000 as a universal definition, in which cardiac troponin (cTn) was the preferred biomarker. A large number of patients formerly classified by creatine kinase (CK) as unstable angina are now ruled-in by cTn as non-ST-elevation myocardial infarction (NSTEMI). METHODS AND RESULTS: The Japanese registry of acute Myocardial INfarction diagnosed by Universal dEfiniTion (J-MINUET) is a prospective and multicenter registry conducted in 28 institutions. We enrolled 3,283 consecutive patients with AMI diagnosed by cTn-based criteria who were admitted to participating institutions within 48 h of symptom onset. There were 2,262 patients (68.9%) with STEMI and 1,021 (31.1%) with NSTEMI. CK was not elevated more than twice the upper limit of normal in 458 patients (44.9%) with NSTEMI (NSTEMI-CK). Although there was no significant difference in the in-hospital mortality of STEMI and NSTEMI with CK elevation (NSTEMI+CK) patients (7.1% vs. 7.8%, P=0.57), it was significantly lower in patients with NSTEMI-CK than in those with STEMI or NSTEMI+CK (1.7%, P<0.001 for each). CONCLUSIONS: J-MINUET revealed the clinical presentation, management and outcomes of Japanese patients with AMI in the current cTn era. We should be aware of the difference between AMI diagnosed by CK-based criteria and AMI diagnosed by cTn-based criteria when using universal definitions for the diagnosis of AMI.
File Format	HTM / HTML
ISSN	13469843
e-ISSN	13474820
Journal	Circulation Journal
Issue Number	6
Volume Number	79
Language	English
Publisher	The Japanese Circulation Society
Publisher Date	2015-01-01
Publisher Place	Japan
Access Restriction	Open
Subject Keyword	Discipline Cardiology Myocardial Infarction Diagnosis Registries Troponin T Blood Angina, Unstable Biological Markers Cohort Studies Comorbidity Coronary Angiography Utilization Coronary Artery Bypass Creatine Kinase Diagnosis, Differential Electrocardiography Heart Failure Epidemiology Etiology Hospital Mortality Hospitalization Mortality Therapy Percutaneous Coronary Intervention Prospective Studies Recurrence Smoking Multicenter Study Observational Study Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Cardiology and Cardiovascular Medicine

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CORRIGENDUM: Clinical Presentation, Management and Outcome of Japanese Patients With Acute Myocardial Infarction in the Troponin Era--Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET).

Preinfarction angina reduces infarct size in ST-elevation myocardial infarction treated with percutaneous coronary intervention.

Acute ST-elevation myocardial infarction in patients hospitalized for noncardiac conditions.

Effects of comorbidity and hospital care on 6-month mortality in patients with elevated cardiac troponin T.

A comprehensive acute coronary syndrome algorithm for centers with percutaneous coronary intervention capability.

Implementation of the third universal definition of myocardial infarction after coronary artery bypass grafting: a survey study in Western Europe.

Impact of Sex on Long-term Mortality From Acute Myocardial Infarction vs Unstable Angina

Left circumflex artery thrombosis in the era of sensitive troponin assays.

Percutaneous Coronary Intervention in Patients Without Acute Myocardial Infarction in China: Results From the China PEACE Prospective Study of Percutaneous Coronary Intervention

Clinical Presentation, Management and Outcome of Japanese Patients With Acute Myocardial Infarction in the Troponin Era - Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET) - .

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CORRIGENDUM: Clinical Presentation, Management and Outcome of Japanese Patients With Acute Myocardial Infarction in the Troponin Era--Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET).

Preinfarction angina reduces infarct size in ST-elevation myocardial infarction treated with percutaneous coronary intervention.

Acute ST-elevation myocardial infarction in patients hospitalized for noncardiac conditions.

Effects of comorbidity and hospital care on 6-month mortality in patients with elevated cardiac troponin T.

A comprehensive acute coronary syndrome algorithm for centers with percutaneous coronary intervention capability.

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