NDLI: Technetium-99m-GSA clearance in mice under long-term dietary restriction.

Please wait, while we are loading the content...

Year: 2017 Volume: 31

Year: 2016 Volume: 30

Year: 2015 Volume: 29

Year: 2014 Volume: 28

Year: 2013 Volume: 27

Year: 2012 Volume: 26

Year: 2011 Volume: 25

Year: 2010 Volume: 24

Year: 2009 Volume: 23

Year: 2009 Volume: 23 Issue: 9

Year: 2009 Volume: 23 Issue: 7

Year: 2009 Volume: 23 Issue: 6

Year: 2009 Volume: 23 Issue: 5

Year: 2009 Volume: 23 Issue: 4

Year: 2009 Volume: 23 Issue: 3

Year: 2009 Volume: 23 Issue: 2

Detection of ectopic gastric mucosa using 99mTc pertechnetate: review of the literature.

Benign ovarian and endometrial uptake on FDG PET-CT: patterns and pitfalls.

An experimental study on the antitumor effect of 131I-17-AAG in vitro and in vivo.

Technetium-99m-GSA clearance in mice under long-term dietary restriction.

Influence of thyroid-stimulating hormone on 18F-fluorodeoxyglucose and 99mTc-methoxyisobutylisonitrile uptake in human poorly differentiated thyroid cancer cells in vitro.

Usefulness of fatty meal-stimulated cholescintigraphy in the diagnosis and treatment of chronic acalculous cholecystitis.

Role of NMDA receptor upon [14C]acetate uptake into intact rat brain.

Biodistribution of immunoliposome labeled with Tc-99m in tumor xenografted mice.

Comparative study of FDG PET/CT and conventional imaging in the staging of rhabdomyosarcoma.

Improvement of likelihood estimation in Logan graphical analysis using maximum a posteriori for neuroreceptor PET imaging.

Gated myocardial perfusion SPECT for preoperative risk stratification in patients with noncardiac vascular disease.

Preliminary study on potential of the jPET-D4 human brain scanner for small animal imaging.

The effect of 18F-FDG-PET/CT respiratory gating on detected metabolic activity in lung lesions.

Combined rest redistribution thallium-201 SPECT and low-dose dobutamine contractility assessment in a simple and practical new viability protocol.

Tc-99m-MIBI scintigraphy in evaluating the effect of hepatocyte growth factor gene therapy for peripheral arteriosclerosis obliterans.

Nuclear medicine practice in Japan: a report of the sixth nationwide survey in 2007.

Year: 2009 Volume: 23 Issue: 1

Year: 2008 Volume: 22

Technetium-99m-GSA clearance in mice under long-term dietary restriction.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Kouda, Katsuyasu Kohno, Hirao Nakamura, Harunobu Ha-Kawa, Sang K. Sonoda, Yoshiaki Iki, Masayuki
Description	Country affiliation: Japan Author Affiliation: Kouda K ( Department of Public Health, Kinki University School of Medicine, 377-2 Ono-Higashi, Osaka-Sayama 589-8511, Japan. kouda@med.kindai.ac.jp)
Abstract	OBJECTIVE: Dietary restriction (DR) without malnutrition is widely acknowledged to prolong lifespan in laboratory animals. Evidence suggests that DR retards age-related decline in protein turnover of most organs. However, there has been no report about hepatic serum glycoprotein catabolism under DR. In the current study, we evaluate the hepatic uptake of asialoglycoprotein in ICR mice with DR by measuring the plasma clearance of technetium-99m galactosyl human serum albumin (Tc-GSA). METHODS: The amount of food supplied to the restricted mice was 70% of that consumed by the mice fed ad libitum (AL). The regimen was initiated at the age of 7 weeks and terminated after the age of 44 weeks. The plasma clearance of Tc-GSA was measured at the age of 7 weeks, 14 weeks, 28 weeks, and 42 weeks. RESULTS: The restricted animals showed a marked decrease in their body and liver weight, and hepatic uptake of Tc-GSA per liver weight in the restricted mice was greater than that in the mice fed AL. On the other hand, the Tc-GSA plasma clearance in the mice fed AL was stable during the study period, and that in the restricted mice showed no change with age either, and those in the two groups were similar. In addition to the receptor function, there was no difference in the expression of mRNAs of the asialoglycoprotein receptor between the two groups. Serum concentrations of cholinesterase and hepatic mRNAs of glutamine synthetase in the restricted mice were higher than those in the mice fed AL. Serum levels of amino acids in the restricted mice were lower than those in the mice fed AL. CONCLUSIONS: The data presented here show that the DR did not affect the capacity of hepatic serum glycoprotein catabolism, whereas several protein metabolic pathways were affected.
File Format	HTM / HTML
ISSN	09147187
Issue Number	2
Volume Number	23
e-ISSN	18646433
Journal	Annals of Nuclear Medicine
Language	English
Publisher	Springer
Publisher Date	2009-02-01
Publisher Place	Japan
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Nuclear Medicine Body Weight Physiology Caloric Restriction Methods Liver Metabolism Technetium Tc 99m Aggregated Albumin Blood Pharmacokinetics Technetium Tc 99m Pentetate Animals Male Metabolic Clearance Rate Mice Mice, Inbred Icr Radiopharmaceuticals Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in