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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Kwon, Chang-Hoon Lee, Chul Young Han, Seung-Jae Kim, Sung-Jae Park, Byung-Chul Jang, Insurk Han, Jeong-Hee |
| Description | Author Affiliation: Kwon CH ( College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Republic of Korea.) |
| Abstract | This study was aimed to evaluate the effect of dietary supplementation of lipid-encapsulated (coated) zinc oxide ZnO on post-weaning diarrhea (colibacillosis) in weaned piglets challenged with enterotoxigenic Escherichia coli (ETEC). Thirty-two 35-day-old weaned piglets were orally challenged with 3 × 10(10) colony forming units of ETEC K88 while eight piglets received no challenge (control). Each eight challenged piglets received a diet containing 100 ppm ZnO (low ZnO), 2500 ppm ZnO (high ZnO) or 100 ppm of lipid (10%)-coated ZnO (coated ZnO) for 7 days; control pigs received the low ZnO diet. Daily gain, goblet cell density in the villi of the duodenum, jejunum and ileum, and villus height in the jejunum and ileum, which decreased due to the challenge, were equally greater in the coated ZnO and high ZnO groups versus low ZnO group. Fecal consistency score, serum interleukin-8 concentration, subjective score of fecal E. coli shedding, and digesta pH in the stomach, jejunum and ileum, which increased due to the challenge, were equally low in the coated ZnO and high ZnO groups versus low ZnO. Results suggest that a low level of coated ZnO might well substitute for a pharmacological level of native ZnO in dietary supplementation to alleviate colibacillosis of weaned piglets. |
| File Format | HTM / HTML |
| ISSN | 13443941 |
| Issue Number | 8 |
| Volume Number | 85 |
| e-ISSN | 17400929 |
| Journal | Animal Science Journal |
| Language | English |
| Publisher | Wiley |
| Publisher Date | 2014-08-01 |
| Publisher Place | Australia |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Veterinary Medicine Diarrhea Therapy Veterinary Dietary Supplements Escherichia Coli Infections Escherichia Coli Gastroenteritis Microbiology Intestines Growth & Development Swine Diseases Swine Zinc Oxide Administration & Dosage Animals Hydrogen-ion Concentration Cytology Weaning Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Agricultural and Biological Sciences |
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