NDLI: Preliminary findings of a previously unrecognized porcine primary immunodeficiency disorder.

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Preliminary findings of a previously unrecognized porcine primary immunodeficiency disorder.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Ozuna, A. G. Cino Rowland, R. R. R. Nietfeld, J. C. Kerrigan, M. A. Dekkers, J. C. M. Wyatt, C. R.
Description	Country affiliation: United States Author Affiliation: Ozuna AG ( Department of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS 66506-5606, USA.)
Abstract	Weaned pigs from a line bred for increased feed efficiency were enrolled in a study of the role of host genes in the response to infection with Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). Four of the pigs were euthanatized early in the study due to weight loss with illness and poor body condition; 2 pigs before PRRSV infection and the other 2 pigs approximately 2 weeks after virus inoculation. The 2 inoculated pigs failed to produce PRRSV-specific antibodies. Gross findings included pneumonia, absence of a detectable thymus, and small secondary lymphoid tissues. Histologically, lymph nodes, spleen, tonsils, and Peyer's patches were sparsely cellular with decreased to absent T and B lymphocytes.
File Format	HTM / HTML
ISSN	03009858
Issue Number	1
Volume Number	50
e-ISSN	15442217
Journal	Veterinary Pathology
Language	English
Publisher	Sage Publication
Publisher Date	2013-01-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Veterinary Medicine Discipline Pathology Immunologic Deficiency Syndromes Veterinary Lymphoid Tissue Pathology Porcine Reproductive And Respiratory Syndrome Immunology Porcine Respiratory And Reproductive Syndrome Virus Isolation & Purification Animals Antibodies, Viral Biosynthesis B-lymphocytes Virology Diagnosis, Differential Lung Lymph Nodes Male Palatine Tonsil Peyer's Patches Pneumonia Genetics Spleen Swine T-lymphocytes Viremia Journal Article Research Support, Non-u.s. Gov't Research Support, U.s. Gov't, Non-p.h.s.
Content Type	Text
Resource Type	Article
Subject	Veterinary

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Comparison of the pathogenesis of single or dual infections with type 1 and type 2 porcine reproductive and respiratory syndrome virus.

Preliminary findings of a previously unrecognized porcine primary immunodeficiency disorder.

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