NDLI: Fundamental concepts in genetics: genetics and the understanding of selection.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Hurst, Laurence D.
Description	Country affiliation: United kingdom Author Affiliation: Hurst LD ( Department of Biology and Biochemistry, University of Bath, Somerset, BA2 7AY, UK. l.d.hurst@bath.ac.uk)
Abstract	At first sight selection is a simple notion, and some consider it the most important evolutionary force. But how important is selection, is it really so trivial to understand and what are the alternatives? Here I discuss how genetics is crucial for addressing all of these questions: genetics allowed the concept of natural selection to become viable, it contributed to our understanding of the complexities of selection and it spurred the development of competing models of evolution. Understanding how and why selection acts has important potential applications, from understanding the mechanisms of disease and microbial resistance, to improving the design of transgenes and drugs.
File Format	HTM / HTML
ISSN	14710056
Issue Number	2
Journal	Nature Reviews Genetics
Volume Number	10
e-ISSN	14710064
Language	English
Publisher	Nature Publishing Group
Publisher Date	2009-02-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Genetics Alleles Genetics, Population Inheritance Patterns Genetics Selection, Genetic Linkage Disequilibrium Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Genetics Molecular Biology Genetics (clinical)

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Fundamental concepts in genetics: genetics and the understanding of selection.