NDLI: Recent advances in genomic DNA sequencing of microbial species from single cells.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Lasken, Roger S. McLean, Jeffrey S.
Description	Country affiliation: United States Author Affiliation: Lasken RS ( J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, California 92037, USA.); McLean JS ( 1] J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, California 92037, USA. [2] School of Dentistry, Department of Periodontics, University of Washington, Seattle, Washington 98195, USA.)
Abstract	The vast majority of microbial species remain uncultivated and, until recently, about half of all known bacterial phyla were identified only from their 16S ribosomal RNA gene sequence. With the advent of single-cell sequencing, genomes of uncultivated species are rapidly filling in unsequenced branches of the microbial phylogenetic tree. The wealth of new insights gained from these previously inaccessible groups is providing a deeper understanding of their basic biology, taxonomy and evolution, as well as their diverse roles in environmental ecosystems and human health.
File Format	HTM / HTML
ISSN	14710056
e-ISSN	14710064
DOI	10.1038/nrg3785
Journal	Nature Reviews Genetics
Issue Number	9
Volume Number	15
Language	English
Publisher	Nature Publishing Group
Publisher Date	2014-09-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Discipline Genetics Bacteria Genetics Genome, Bacterial Genomics Microbiota Sequence Analysis, Dna Classification Dna, Bacterial Chemistry Dna, Ribosomal Evolution, Molecular Genetic Variation Phylogeny Rna, Ribosomal, 16s Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Genetics Molecular Biology Genetics (clinical)

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