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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Rosen, Clifford J. Taylor, Christine L. |
| Description | Country affiliation: United States Author Affiliation: Rosen CJ ( Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME 04074, USA. crofen@gmail.com) |
| Abstract | Misconceptions about vitamin D continue to grow despite publications in the past few years that have attempted to clarify risk. We present our perspective, and offer several conclusions. Calcium and vitamin D supplementation can reduce fracture risk by â¼10%. On the other hand, little evidence exists to support a threshold measure for vitamin D status (serum levels of 25-hydroxyvitamin D) above which fractures are reduced. The association of serum concentrations of 25-hydroxyvitamin D with other chronic diseases is confounded by multiple factors and conflicting outcomes that cannot be used to support a causal association. High doses of vitamin D supplements might not be completely harmless and should be avoided until additional data becomes available. Similarly, scant rationale exists for aggressive vitamin D supplementation for pregnant or lactating women. Dispelling misconceptions about vitamin D will ultimately benefit health-care providers and patients alike. |
| File Format | HTM / HTML |
| ISSN | 17595029 |
| Issue Number | 7 |
| Volume Number | 9 |
| e-ISSN | 17595037 |
| Journal | Nature Reviews Endocrinology |
| Language | English |
| Publisher | Nature Publishing Group |
| Publisher Date | 2013-07-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Endocrinology Vitamin D Therapeutic Use Dietary Supplements Humans Osteoporosis Blood Drug Therapy Adverse Effects Analogs & Derivatives Vitamin D Deficiency Complications Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Endocrinology, Diabetes and Metabolism Endocrinology |
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